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Transhepatic intravascular ultrasound for evaluation of portal venous involvement in patients with cancer of the pancreatic head region.

Hannesson, P H; Lundstedt, C; Dawiskiba, Sigmund LU ; Stridbeck, Hans LU and Ihse, Ingemar LU (2002) In European Radiology 12(5). p.1150-1154
Abstract
The aim of this study was to evaluate the ability of intravascular ultrasound to diagnose tumor involvement of the portal and the superior mesenteric veins using the preoperative percutaneous, transhepatic approach, and to compare the findings with those made at concomitant direct portography, surgery, and histopathological examination. Ten patients with a preoperative diagnosis of a resectable tumor in the pancreatic head region were examined with percutaneous transhepatic portography (PTP) and intravascular ultrasound (IVUS). The surgeon's intraoperative evaluation and the histopathological examination in combination revealed tumor involvement of the portal or superior mesenteric veins in six of the ten patients. Percutaneous... (More)
The aim of this study was to evaluate the ability of intravascular ultrasound to diagnose tumor involvement of the portal and the superior mesenteric veins using the preoperative percutaneous, transhepatic approach, and to compare the findings with those made at concomitant direct portography, surgery, and histopathological examination. Ten patients with a preoperative diagnosis of a resectable tumor in the pancreatic head region were examined with percutaneous transhepatic portography (PTP) and intravascular ultrasound (IVUS). The surgeon's intraoperative evaluation and the histopathological examination in combination revealed tumor involvement of the portal or superior mesenteric veins in six of the ten patients. Percutaneous transhepatic portography suggested tumor involvement of the veins in six patients but two of the examinations were false positive and another two were false negative. Intravascular ultrasound showed signs of tumor involvement in eight patients. The examination was, however, false positive in two patients, but there were no false negatives. Complications of the percutaneous transhepatic procedure occurred in six patients including severe pain, bleeding, and related death. Percutaneous transhepatic IVUS of the portal vein may be a useful tool in the preoperative selection of the subgroup of patients with tumor of the pancreatic head region that could benefit from surgery. There is a need for technical improvement as well as studies with larger patient series to definitely decide the role of the technique. (Less)
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organization
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type
Contribution to journal
publication status
published
subject
keywords
Pancreatic Neoplasms : surgery, Pancreatic Neoplasms : pathology, Middle Age, Mesenteric Veins : ultrastructure, Mesenteric Veins : pathology, Male, Human, Female, False Positive Reactions, False Negative Reactions, Comparative Study, Aged, Adult, Portography, Pancreatic Neoplasms : ultrasonography, Portal Vein : pathology, Portal Vein : ultrasonography
in
European Radiology
volume
12
issue
5
pages
1150 - 1154
publisher
Springer
external identifiers
  • wos:000175613700023
  • pmid:11976861
  • scopus:0036584768
ISSN
0938-7994
DOI
10.1007/s00330-001-1210-4
language
English
LU publication?
yes
id
d3accd27-5c43-4e32-8374-a71dc41523ef (old id 107834)
alternative location
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11976861&dopt=Abstract
date added to LUP
2007-07-18 13:58:50
date last changed
2017-01-01 05:12:25
@article{d3accd27-5c43-4e32-8374-a71dc41523ef,
  abstract     = {The aim of this study was to evaluate the ability of intravascular ultrasound to diagnose tumor involvement of the portal and the superior mesenteric veins using the preoperative percutaneous, transhepatic approach, and to compare the findings with those made at concomitant direct portography, surgery, and histopathological examination. Ten patients with a preoperative diagnosis of a resectable tumor in the pancreatic head region were examined with percutaneous transhepatic portography (PTP) and intravascular ultrasound (IVUS). The surgeon's intraoperative evaluation and the histopathological examination in combination revealed tumor involvement of the portal or superior mesenteric veins in six of the ten patients. Percutaneous transhepatic portography suggested tumor involvement of the veins in six patients but two of the examinations were false positive and another two were false negative. Intravascular ultrasound showed signs of tumor involvement in eight patients. The examination was, however, false positive in two patients, but there were no false negatives. Complications of the percutaneous transhepatic procedure occurred in six patients including severe pain, bleeding, and related death. Percutaneous transhepatic IVUS of the portal vein may be a useful tool in the preoperative selection of the subgroup of patients with tumor of the pancreatic head region that could benefit from surgery. There is a need for technical improvement as well as studies with larger patient series to definitely decide the role of the technique.},
  author       = {Hannesson, P H and Lundstedt, C and Dawiskiba, Sigmund and Stridbeck, Hans and Ihse, Ingemar},
  issn         = {0938-7994},
  keyword      = {Pancreatic Neoplasms : surgery,Pancreatic Neoplasms : pathology,Middle Age,Mesenteric Veins : ultrastructure,Mesenteric Veins : pathology,Male,Human,Female,False Positive Reactions,False Negative Reactions,Comparative Study,Aged,Adult,Portography,Pancreatic Neoplasms : ultrasonography,Portal Vein : pathology,Portal Vein : ultrasonography},
  language     = {eng},
  number       = {5},
  pages        = {1150--1154},
  publisher    = {Springer},
  series       = {European Radiology},
  title        = {Transhepatic intravascular ultrasound for evaluation of portal venous involvement in patients with cancer of the pancreatic head region.},
  url          = {http://dx.doi.org/10.1007/s00330-001-1210-4},
  volume       = {12},
  year         = {2002},
}