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Uterine artery score and perinatal outcome.

Hernandez-Andrade, Edgar LU ; Brodszki, Jana LU ; Lingman, Göran LU ; Gudmundsson, Saemundur LU ; Molin, Johan LU and Marsal, Karel LU (2002) In Ultrasound in Obstetrics & Gynecology 19(5). p.438-442
Abstract
OBJECTIVE: To evaluate a modified uterine artery score based on the pulsatility index and presence or absence of notching in the Doppler velocity waveform recorded from both uterine arteries in relation to the perinatal outcome. METHODS: A retrospective analysis was performed in 741 third-trimester high-risk pregnancies. The uterine artery score was constructed assigning one point to each abnormal parameter-high pulsatility index and presence of notch-thus ranging from 0 (normal findings in both uterine arteries) to 4 (notch and high pulsatility index in both uterine arteries). In a subgroup with lateral placenta (n = 359), two definitions of abnormal pulsatility index were compared. In the uniform uterine artery score, a pulsatility index... (More)
OBJECTIVE: To evaluate a modified uterine artery score based on the pulsatility index and presence or absence of notching in the Doppler velocity waveform recorded from both uterine arteries in relation to the perinatal outcome. METHODS: A retrospective analysis was performed in 741 third-trimester high-risk pregnancies. The uterine artery score was constructed assigning one point to each abnormal parameter-high pulsatility index and presence of notch-thus ranging from 0 (normal findings in both uterine arteries) to 4 (notch and high pulsatility index in both uterine arteries). In a subgroup with lateral placenta (n = 359), two definitions of abnormal pulsatility index were compared. In the uniform uterine artery score, a pulsatility index > 1.20 in both uterine arteries was considered abnormal, disregarding the placental location; in the subgroup with lateral placenta, the high pulsatility index was defined as > 1.00 on the placental side and > 1.40 on the non-placental side. RESULTS: Receiver-operating characteristic curves did not reveal any difference in the diagnostic capacity between the group with a uniform uterine artery score and the subgroup with lateral placenta (P = 0.54). In the total material, the odds ratios and linear regression analysis showed an increased risk for an adverse perinatal outcome with increasing uterine artery score (P < 0.01). At a uterine artery score > 2, there was a significantly increased risk for operative delivery for fetal distress, neonatal intensive care unit admission, 5-min Apgar score < 7, preterm delivery and delivery of a small-for-gestational age fetus. CONCLUSION: In high-risk third-trimester pregnancies, Doppler velocity waveforms of the uterine arteries can be evaluated using the uterine artery score disregarding the placental location. The uterine artery score possesses a high predictive value regarding adverse perinatal outcome. (Less)
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published
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keywords
Comparative Study, Female, Human, Confidence Intervals, Odds Ratio, Predictive Value of Tests, Pregnancy, Pregnancy Outcome, Pregnancy Trimester, Third, High-Risk, Retrospective Studies, Sensitivity and Specificity, Support, Non-U.S. Gov't, Ultrasonography, Doppler, Prenatal : methods, Uterus : physiopathology, Blood Flow Velocity, Adult, Arteries : ultrasonography
in
Ultrasound in Obstetrics & Gynecology
volume
19
issue
5
pages
438 - 442
publisher
John Wiley & Sons
external identifiers
  • wos:000176106100003
  • pmid:11982974
  • scopus:0036091240
ISSN
1469-0705
DOI
10.1046/j.1469-0705.2002.00665.x
language
English
LU publication?
yes
id
824d59d8-c725-4383-8a78-48c94c4ea566 (old id 107940)
alternative location
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11982974&dopt=Abstract
date added to LUP
2007-07-18 08:32:43
date last changed
2017-08-13 04:29:51
@article{824d59d8-c725-4383-8a78-48c94c4ea566,
  abstract     = {OBJECTIVE: To evaluate a modified uterine artery score based on the pulsatility index and presence or absence of notching in the Doppler velocity waveform recorded from both uterine arteries in relation to the perinatal outcome. METHODS: A retrospective analysis was performed in 741 third-trimester high-risk pregnancies. The uterine artery score was constructed assigning one point to each abnormal parameter-high pulsatility index and presence of notch-thus ranging from 0 (normal findings in both uterine arteries) to 4 (notch and high pulsatility index in both uterine arteries). In a subgroup with lateral placenta (n = 359), two definitions of abnormal pulsatility index were compared. In the uniform uterine artery score, a pulsatility index &gt; 1.20 in both uterine arteries was considered abnormal, disregarding the placental location; in the subgroup with lateral placenta, the high pulsatility index was defined as &gt; 1.00 on the placental side and &gt; 1.40 on the non-placental side. RESULTS: Receiver-operating characteristic curves did not reveal any difference in the diagnostic capacity between the group with a uniform uterine artery score and the subgroup with lateral placenta (P = 0.54). In the total material, the odds ratios and linear regression analysis showed an increased risk for an adverse perinatal outcome with increasing uterine artery score (P &lt; 0.01). At a uterine artery score &gt; 2, there was a significantly increased risk for operative delivery for fetal distress, neonatal intensive care unit admission, 5-min Apgar score &lt; 7, preterm delivery and delivery of a small-for-gestational age fetus. CONCLUSION: In high-risk third-trimester pregnancies, Doppler velocity waveforms of the uterine arteries can be evaluated using the uterine artery score disregarding the placental location. The uterine artery score possesses a high predictive value regarding adverse perinatal outcome.},
  author       = {Hernandez-Andrade, Edgar and Brodszki, Jana and Lingman, Göran and Gudmundsson, Saemundur and Molin, Johan and Marsal, Karel},
  issn         = {1469-0705},
  keyword      = {Comparative Study,Female,Human,Confidence Intervals,Odds Ratio,Predictive Value of Tests,Pregnancy,Pregnancy Outcome,Pregnancy Trimester,Third,High-Risk,Retrospective Studies,Sensitivity and Specificity,Support,Non-U.S. Gov't,Ultrasonography,Doppler,Prenatal : methods,Uterus : physiopathology,Blood Flow Velocity,Adult,Arteries : ultrasonography},
  language     = {eng},
  number       = {5},
  pages        = {438--442},
  publisher    = {John Wiley & Sons},
  series       = {Ultrasound in Obstetrics & Gynecology},
  title        = {Uterine artery score and perinatal outcome.},
  url          = {http://dx.doi.org/10.1046/j.1469-0705.2002.00665.x},
  volume       = {19},
  year         = {2002},
}