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A polymer neural probe with tunable flexibility

Ejserholm, Fredrik LU ; Vastesson, A.; Haraldsson, T.; van der Wijngaart, W.; Schouenborg, J.; Wallman, Lars LU and Bengtsson, Martin LU (2013) 6th International IEEE EMBS Conference on Neural Engineering (NER) p.691-694
Abstract
A novel polymeric material, off-stoichiometry thiol-ene-epoxy (OSTE+), has been evaluated for the fabrication of neural implants. OSTE+ is easily photo-structurable and exhibits mechanical properties suitable for stable implantation of the probe into brain tissue, while being sufficiently soft at physiological temperatures to reduce living tissue damage. The facile processing of OSTE+ allows use in applications where SU-8 or polyimide currently are the materials of choice. Uniquely, OSTE+ has a Young's modulus of 1.9 GPa at 10 degrees C decreasing almost two orders of magnitude to 30 MPa at 40 degrees C, which can be compared to the Young's modulus of 2.1 GPa for SU-8. We show a probe, with nine gold electrode sites, implanted into 0.5%... (More)
A novel polymeric material, off-stoichiometry thiol-ene-epoxy (OSTE+), has been evaluated for the fabrication of neural implants. OSTE+ is easily photo-structurable and exhibits mechanical properties suitable for stable implantation of the probe into brain tissue, while being sufficiently soft at physiological temperatures to reduce living tissue damage. The facile processing of OSTE+ allows use in applications where SU-8 or polyimide currently are the materials of choice. Uniquely, OSTE+ has a Young's modulus of 1.9 GPa at 10 degrees C decreasing almost two orders of magnitude to 30 MPa at 40 degrees C, which can be compared to the Young's modulus of 2.1 GPa for SU-8. We show a probe, with nine gold electrode sites, implanted into 0.5% agar at 40 degrees C using active cooling during the implantation. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
2013 6th International IEEE/Embs Conference on Neural Engineering (NER)
pages
691 - 694
publisher
IEEE--Institute of Electrical and Electronics Engineers Inc.
conference name
6th International IEEE EMBS Conference on Neural Engineering (NER)
conference location
San Diego, CA
conference dates
2013-11-06 - 2013-11-08
external identifiers
  • wos:000331259200173
  • scopus:84897675358
ISSN
1948-3546
DOI
10.1109/NER.2013.6696028
language
English
LU publication?
yes
id
108242c8-6d97-4026-9909-db7a3f0e2ec1 (old id 4367221)
date added to LUP
2014-06-27 08:29:39
date last changed
2019-01-06 07:35:52
@inproceedings{108242c8-6d97-4026-9909-db7a3f0e2ec1,
  abstract     = {A novel polymeric material, off-stoichiometry thiol-ene-epoxy (OSTE+), has been evaluated for the fabrication of neural implants. OSTE+ is easily photo-structurable and exhibits mechanical properties suitable for stable implantation of the probe into brain tissue, while being sufficiently soft at physiological temperatures to reduce living tissue damage. The facile processing of OSTE+ allows use in applications where SU-8 or polyimide currently are the materials of choice. Uniquely, OSTE+ has a Young's modulus of 1.9 GPa at 10 degrees C decreasing almost two orders of magnitude to 30 MPa at 40 degrees C, which can be compared to the Young's modulus of 2.1 GPa for SU-8. We show a probe, with nine gold electrode sites, implanted into 0.5% agar at 40 degrees C using active cooling during the implantation.},
  author       = {Ejserholm, Fredrik and Vastesson, A. and Haraldsson, T. and van der Wijngaart, W. and Schouenborg, J. and Wallman, Lars and Bengtsson, Martin},
  issn         = {1948-3546},
  language     = {eng},
  location     = {San Diego, CA},
  pages        = {691--694},
  publisher    = {IEEE--Institute of Electrical and Electronics Engineers Inc.},
  title        = {A polymer neural probe with tunable flexibility},
  url          = {http://dx.doi.org/10.1109/NER.2013.6696028},
  year         = {2013},
}