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NSAID visar övertygande effekt vid postoperativ smärta

Engström, Martin LU and Naesh, Ole LU (2002) In Läkartidningen 99(19). p.9-2164
Abstract
Non-steroidal antiinflammatory drugs (NSAID) are increasingly being included in the management of postoperative pain as part of a multimodal therapeutic approach. However, there is an ongoing debate among clinicians as to the perioperative use of NSAID's as many authors have cautioned against their use in this setting. Concerns about their impact on coagulation and renal function as well as a risk for gastrointestinal bleeding have been raised. However, many of the adverse effects reported have occurred during long term treatment and might not be directly applicable to the perioperative period. Still the clinician must be aware of the potential risks and benefits of these drugs. This review focuses on the pro's and con's of perioperative... (More)
Non-steroidal antiinflammatory drugs (NSAID) are increasingly being included in the management of postoperative pain as part of a multimodal therapeutic approach. However, there is an ongoing debate among clinicians as to the perioperative use of NSAID's as many authors have cautioned against their use in this setting. Concerns about their impact on coagulation and renal function as well as a risk for gastrointestinal bleeding have been raised. However, many of the adverse effects reported have occurred during long term treatment and might not be directly applicable to the perioperative period. Still the clinician must be aware of the potential risks and benefits of these drugs. This review focuses on the pro's and con's of perioperative NSAID usage. We address the background for a multimodal approach to postoperative pain relief as well as potential alternatives to NSAID's and the recently introduced COX2-selective inhibitors. (Less)
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author
organization
alternative title
NSAID demonstrate convincing effect on postoperative pain
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Kidney Failure, Human, Non-Steroidal : adverse effects, Anti-Inflammatory Agents, Non-Steroidal : contraindications, Cyclooxygenase Inhibitors : administration & dosage, Cyclooxygenase Inhibitors : adverse effects, Drug Hypersensitivity : etiology, English Abstract, Gastrointestinal Hemorrhage : chemically induced, Non-Steroidal : administration & dosage, Cyclooxygenase Inhibitors : contraindications, Acute : chemically induced, Pain, Postoperative : drug therapy, Postoperative : prevention & control, Platelet Aggregation : drug effects
in
Läkartidningen
volume
99
issue
19
pages
9 - 2164
publisher
Swedish Medical Association
external identifiers
  • pmid:12082932
  • scopus:0037041975
ISSN
0023-7205
language
Swedish
LU publication?
yes
id
f20fc86c-0701-4d31-8403-cc0afc2e32fd (old id 109034)
alternative location
http://ltarkiv.lakartidningen.se/artNo24783
date added to LUP
2007-06-28 08:49:27
date last changed
2017-01-01 07:08:55
@article{f20fc86c-0701-4d31-8403-cc0afc2e32fd,
  abstract     = {Non-steroidal antiinflammatory drugs (NSAID) are increasingly being included in the management of postoperative pain as part of a multimodal therapeutic approach. However, there is an ongoing debate among clinicians as to the perioperative use of NSAID's as many authors have cautioned against their use in this setting. Concerns about their impact on coagulation and renal function as well as a risk for gastrointestinal bleeding have been raised. However, many of the adverse effects reported have occurred during long term treatment and might not be directly applicable to the perioperative period. Still the clinician must be aware of the potential risks and benefits of these drugs. This review focuses on the pro's and con's of perioperative NSAID usage. We address the background for a multimodal approach to postoperative pain relief as well as potential alternatives to NSAID's and the recently introduced COX2-selective inhibitors.},
  author       = {Engström, Martin and Naesh, Ole},
  issn         = {0023-7205},
  keyword      = {Kidney Failure,Human,Non-Steroidal : adverse effects,Anti-Inflammatory Agents,Non-Steroidal : contraindications,Cyclooxygenase Inhibitors : administration & dosage,Cyclooxygenase Inhibitors : adverse effects,Drug Hypersensitivity : etiology,English Abstract,Gastrointestinal Hemorrhage : chemically induced,Non-Steroidal : administration & dosage,Cyclooxygenase Inhibitors : contraindications,Acute : chemically induced,Pain,Postoperative : drug therapy,Postoperative : prevention & control,Platelet Aggregation : drug effects},
  language     = {swe},
  number       = {19},
  pages        = {9--2164},
  publisher    = {Swedish Medical Association},
  series       = {Läkartidningen},
  title        = {NSAID visar övertygande effekt vid postoperativ smärta},
  volume       = {99},
  year         = {2002},
}