5-y Follow-up study of patients with neuroborreliosis.
(2002) In Scandinavian Journal of Infectious Diseases 34(6). p.421-425- Abstract
- The objective of this follow-up study was to determine the long-term outcome of strictly classified cases of neuroborreliosis treated with antibiotics. A 1-y prospective population-based survey of Lyme borreliosis was conducted in southern Sweden between 1992 and 1993. A total of 349 identified cases with suspected neuroborreliosis were followed up 5 y later. Medical records were reviewed and all participants filled in a questionnaire. Of those patients classified with definite neuroborreliosis, 114/130 completed the follow-up, of whom 111 had completed the initial antibiotic treatment. Of the 114 patients followed up, 86 (75%) had recovered completely and 70 (61%) had recovered within 6 months. Residual neurological symptoms, such as... (More)
- The objective of this follow-up study was to determine the long-term outcome of strictly classified cases of neuroborreliosis treated with antibiotics. A 1-y prospective population-based survey of Lyme borreliosis was conducted in southern Sweden between 1992 and 1993. A total of 349 identified cases with suspected neuroborreliosis were followed up 5 y later. Medical records were reviewed and all participants filled in a questionnaire. Of those patients classified with definite neuroborreliosis, 114/130 completed the follow-up, of whom 111 had completed the initial antibiotic treatment. Of the 114 patients followed up, 86 (75%) had recovered completely and 70 (61%) had recovered within 6 months. Residual neurological symptoms, such as facial palsy, concentration disorder, paresthesia and/or neuropathy, were reported by 28/114 patients. No significant differences between different antibiotic treatments were observed in terms of the occurrence of sequelae. To conclude, we found that 25% (95% confidence interval 17-33%) of the patients suffered from residual neurological symptoms 5 y post-treatment. However, the clinical outcome of treated neuroborreliosis is favorable as only 14/114 (12%) patients had sequelae that influenced their daily activities post-treatment. Early diagnosis and treatment would seem to be of great importance in order to avoid such sequelae. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/109733
- author
- Berglund, Johan LU ; Stjernberg, Louise LU ; Ornstein, Katharina LU ; Tykesson-Joelsson, Katarina and Walter, Hallstein
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scandinavian Journal of Infectious Diseases
- volume
- 34
- issue
- 6
- pages
- 421 - 425
- publisher
- Informa Healthcare
- external identifiers
-
- pmid:12160168
- wos:000177058300005
- scopus:0035990579
- ISSN
- 1651-1980
- DOI
- 10.1080/00365540110080421
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Infectious Diseases Research Unit (013242010), Community Medicine (013241810), Department of Clinical Sciences, Malmö (013240000), Division of Infection Medicine (SUS) (013008000)
- id
- 8fdfb752-38e1-486f-9c8d-ba2cbb9393a3 (old id 109733)
- alternative location
- http://www.informaworld.com/smpp/content?content=10.1080/00365540110080421
- date added to LUP
- 2016-04-01 17:14:57
- date last changed
- 2022-02-20 19:36:27
@article{8fdfb752-38e1-486f-9c8d-ba2cbb9393a3,
abstract = {{The objective of this follow-up study was to determine the long-term outcome of strictly classified cases of neuroborreliosis treated with antibiotics. A 1-y prospective population-based survey of Lyme borreliosis was conducted in southern Sweden between 1992 and 1993. A total of 349 identified cases with suspected neuroborreliosis were followed up 5 y later. Medical records were reviewed and all participants filled in a questionnaire. Of those patients classified with definite neuroborreliosis, 114/130 completed the follow-up, of whom 111 had completed the initial antibiotic treatment. Of the 114 patients followed up, 86 (75%) had recovered completely and 70 (61%) had recovered within 6 months. Residual neurological symptoms, such as facial palsy, concentration disorder, paresthesia and/or neuropathy, were reported by 28/114 patients. No significant differences between different antibiotic treatments were observed in terms of the occurrence of sequelae. To conclude, we found that 25% (95% confidence interval 17-33%) of the patients suffered from residual neurological symptoms 5 y post-treatment. However, the clinical outcome of treated neuroborreliosis is favorable as only 14/114 (12%) patients had sequelae that influenced their daily activities post-treatment. Early diagnosis and treatment would seem to be of great importance in order to avoid such sequelae.}},
author = {{Berglund, Johan and Stjernberg, Louise and Ornstein, Katharina and Tykesson-Joelsson, Katarina and Walter, Hallstein}},
issn = {{1651-1980}},
language = {{eng}},
number = {{6}},
pages = {{421--425}},
publisher = {{Informa Healthcare}},
series = {{Scandinavian Journal of Infectious Diseases}},
title = {{5-y Follow-up study of patients with neuroborreliosis.}},
url = {{http://dx.doi.org/10.1080/00365540110080421}},
doi = {{10.1080/00365540110080421}},
volume = {{34}},
year = {{2002}},
}