A longitudinal cohort study on the prevalence of Helicobacter pylori antibodies in Swedish children and adolescents.
(2002) In Acta Pædiatrica 91(6). p.636-640- Abstract
- The aim of this study was to monitor the Helicobacter pylori antibody seroprevalence of an asymptomatic cohort between the ages of 4 and 18 y. The H. pylori antibody titres in a longitudinally followed cohort of 168 native Swedish children (born between 1972 and 1974) were established at 4, 8, 12, 16, and 18 y of age. Seventeen children (10.1%) were found positive on at least one occasion when a paediatric cut-off was applied. Five children (3.0%) reached levels considered positive in adults. The seroprevalence at 4 y of age was 4.0%, at 8 y 2.5%, at 12 y 4.9%, at 16 y 5.3%, and at 18 y 6.3%. The difference in serological titres between the age groups was not significant. A change from negative to positive after the age of 4 took place in... (More)
- The aim of this study was to monitor the Helicobacter pylori antibody seroprevalence of an asymptomatic cohort between the ages of 4 and 18 y. The H. pylori antibody titres in a longitudinally followed cohort of 168 native Swedish children (born between 1972 and 1974) were established at 4, 8, 12, 16, and 18 y of age. Seventeen children (10.1%) were found positive on at least one occasion when a paediatric cut-off was applied. Five children (3.0%) reached levels considered positive in adults. The seroprevalence at 4 y of age was 4.0%, at 8 y 2.5%, at 12 y 4.9%, at 16 y 5.3%, and at 18 y 6.3%. The difference in serological titres between the age groups was not significant. A change from negative to positive after the age of 4 took place in 5 of the cases. Spontaneous seroreversion appeared in 5 cases. CONCLUSION: Our findings showed no significant differences among the various age groups. Seventeen of the 168 children (10.1%) had been infected at some time, the prevalence ranging from 2.5% to 6.3%. Seroconversion and seroreversion occurred infrequently between the ages of 4 and 18 y. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/109755
- author
- Granquist, Å ; Bredberg, A ; Sveger, Tomas LU and Axelsson, Irene LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Pædiatrica
- volume
- 91
- issue
- 6
- pages
- 636 - 640
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000176674400005
- pmid:12162593
- scopus:0036049386
- ISSN
- 1651-2227
- DOI
- 10.1080/080352502760069025
- language
- English
- LU publication?
- yes
- id
- d6b92d14-a8e8-47ba-887a-e73f24dc4299 (old id 109755)
- date added to LUP
- 2016-04-01 15:59:37
- date last changed
- 2023-06-05 04:00:37
@article{d6b92d14-a8e8-47ba-887a-e73f24dc4299,
abstract = {{The aim of this study was to monitor the Helicobacter pylori antibody seroprevalence of an asymptomatic cohort between the ages of 4 and 18 y. The H. pylori antibody titres in a longitudinally followed cohort of 168 native Swedish children (born between 1972 and 1974) were established at 4, 8, 12, 16, and 18 y of age. Seventeen children (10.1%) were found positive on at least one occasion when a paediatric cut-off was applied. Five children (3.0%) reached levels considered positive in adults. The seroprevalence at 4 y of age was 4.0%, at 8 y 2.5%, at 12 y 4.9%, at 16 y 5.3%, and at 18 y 6.3%. The difference in serological titres between the age groups was not significant. A change from negative to positive after the age of 4 took place in 5 of the cases. Spontaneous seroreversion appeared in 5 cases. CONCLUSION: Our findings showed no significant differences among the various age groups. Seventeen of the 168 children (10.1%) had been infected at some time, the prevalence ranging from 2.5% to 6.3%. Seroconversion and seroreversion occurred infrequently between the ages of 4 and 18 y.}},
author = {{Granquist, Å and Bredberg, A and Sveger, Tomas and Axelsson, Irene}},
issn = {{1651-2227}},
language = {{eng}},
number = {{6}},
pages = {{636--640}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Pædiatrica}},
title = {{A longitudinal cohort study on the prevalence of Helicobacter pylori antibodies in Swedish children and adolescents.}},
url = {{http://dx.doi.org/10.1080/080352502760069025}},
doi = {{10.1080/080352502760069025}},
volume = {{91}},
year = {{2002}},
}