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The relationship between different forms of human alpha-mannosidase

Chester, Alan LU ; Lundblad, A and Masson, P K (1975) In Biochimica et Biophysica Acta 391(2). p.341-348
Abstract
The tissue distribution and some properties of human alpha-mannosidase (alpha-D-mannoside mannohydrolase EC 3.2.1.24) have been studied. The acidic forms of the enzyme were fairly stable, whereas the neutral forms easily lost enzymic activity. The acidic forms were sensitive to neuraminidase but the neutral forms were unaffected. The experiments indicate that the acidic components are closely related to each other, differing only in sialic acid content and possibly conformation. The neutral forms of the enzyme are probably quite different from the acidic forms both in structure and cellular function.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Biochimica et Biophysica Acta
volume
391
issue
2
pages
341 - 348
publisher
Elsevier
external identifiers
  • pmid:238600
ISSN
0006-3002
language
English
LU publication?
yes
id
6b223d90-fbd9-43c5-b91b-81d3628971d5 (old id 1102584)
date added to LUP
2008-08-14 12:55:46
date last changed
2016-04-16 03:05:18
@article{6b223d90-fbd9-43c5-b91b-81d3628971d5,
  abstract     = {The tissue distribution and some properties of human alpha-mannosidase (alpha-D-mannoside mannohydrolase EC 3.2.1.24) have been studied. The acidic forms of the enzyme were fairly stable, whereas the neutral forms easily lost enzymic activity. The acidic forms were sensitive to neuraminidase but the neutral forms were unaffected. The experiments indicate that the acidic components are closely related to each other, differing only in sialic acid content and possibly conformation. The neutral forms of the enzyme are probably quite different from the acidic forms both in structure and cellular function.},
  author       = {Chester, Alan and Lundblad, A and Masson, P K},
  issn         = {0006-3002},
  language     = {eng},
  number       = {2},
  pages        = {341--348},
  publisher    = {Elsevier},
  series       = {Biochimica et Biophysica Acta},
  title        = {The relationship between different forms of human alpha-mannosidase},
  volume       = {391},
  year         = {1975},
}