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Infection with delta agent in Sweden: introduction of a new hepatitis agent

Hansson, B G; Moestrup, T; Widell, Anders LU and Nordenfelt, E (1982) In Journal of Infectious Diseases 146(4). p.472-478
Abstract
To investigate the epidemiology of infection with delta (delta) agent in a Swedish city, 181 chronic carriers of hepatitis B surface antigen (HBsAg) and 599 patients with acute, self-limited hepatitis B were analyzed for delta antigen and antibody to delta antigen (anti-delta). The study covered the period from 1970 to 1981. The delta agent was found to have been introduced to this population in 1973. Markers of infection with delta agent were almost exclusively found in intravenous drug addicts and their close contacts. The proportion of drug addicts who were chronic HBsAg carriers with anti-delta increased with time and reached 72% in 1979-1981. An episode of acute hepatitis was frequently seen in connection with seroconversion to... (More)
To investigate the epidemiology of infection with delta (delta) agent in a Swedish city, 181 chronic carriers of hepatitis B surface antigen (HBsAg) and 599 patients with acute, self-limited hepatitis B were analyzed for delta antigen and antibody to delta antigen (anti-delta). The study covered the period from 1970 to 1981. The delta agent was found to have been introduced to this population in 1973. Markers of infection with delta agent were almost exclusively found in intravenous drug addicts and their close contacts. The proportion of drug addicts who were chronic HBsAg carriers with anti-delta increased with time and reached 72% in 1979-1981. An episode of acute hepatitis was frequently seen in connection with seroconversion to anti-delta. Among the domestic cases of acute, self-limited hepatitis, no simultaneous infections with hepatitis B virus and delta agent were found before 1975. From 1975 to 1980, between 18% and 44% of the drug addicts with acute hepatitis B were also infected with delta agent. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Infectious Diseases
volume
146
issue
4
pages
472 - 478
publisher
Oxford University Press
external identifiers
  • pmid:7119477
  • scopus:0019937051
ISSN
1537-6613
language
English
LU publication?
yes
id
0b984505-bffc-422b-a2ca-39e0f8a48edc (old id 1102900)
date added to LUP
2008-08-13 13:26:43
date last changed
2017-08-06 04:30:29
@article{0b984505-bffc-422b-a2ca-39e0f8a48edc,
  abstract     = {To investigate the epidemiology of infection with delta (delta) agent in a Swedish city, 181 chronic carriers of hepatitis B surface antigen (HBsAg) and 599 patients with acute, self-limited hepatitis B were analyzed for delta antigen and antibody to delta antigen (anti-delta). The study covered the period from 1970 to 1981. The delta agent was found to have been introduced to this population in 1973. Markers of infection with delta agent were almost exclusively found in intravenous drug addicts and their close contacts. The proportion of drug addicts who were chronic HBsAg carriers with anti-delta increased with time and reached 72% in 1979-1981. An episode of acute hepatitis was frequently seen in connection with seroconversion to anti-delta. Among the domestic cases of acute, self-limited hepatitis, no simultaneous infections with hepatitis B virus and delta agent were found before 1975. From 1975 to 1980, between 18% and 44% of the drug addicts with acute hepatitis B were also infected with delta agent.},
  author       = {Hansson, B G and Moestrup, T and Widell, Anders and Nordenfelt, E},
  issn         = {1537-6613},
  language     = {eng},
  number       = {4},
  pages        = {472--478},
  publisher    = {Oxford University Press},
  series       = {Journal of Infectious Diseases},
  title        = {Infection with delta agent in Sweden: introduction of a new hepatitis agent},
  volume       = {146},
  year         = {1982},
}