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Desensitisation as a means of preventing untoward reactions to ionic contrast media

Agardh, Carl-David LU ; Arner, B; Ekholm, S and Boijsen, E (1983) In Acta radiologica: diagnosis 24(3). p.235-239
Abstract
Patients with a previous history of anaphylactic reactions to ionic iodinated contrast media were desensitised before a second radiologic examination was performed. The tolerance to the contrast medium was raised by repeated intravenous injections in increasing doses and concentrations. No serious side effects were noted when the examinations with contrast medium was repeated within a few days after the desensitisation. The positive effect of the desensitisation may depend on a successive consumption of complement proteins, probably responsible for the allergic reactions. Therefore, the available amount of complement for some days may be too low for the occurrence of a complement reaction.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta radiologica: diagnosis
volume
24
issue
3
pages
235 - 239
publisher
John Wiley & Sons
external identifiers
  • pmid:6624527
  • scopus:0020554387
ISSN
0567-8056
language
English
LU publication?
yes
id
1376f2fc-56d7-4881-9930-23d1fe50f93e (old id 1103065)
date added to LUP
2008-08-13 09:18:13
date last changed
2017-02-26 04:07:38
@article{1376f2fc-56d7-4881-9930-23d1fe50f93e,
  abstract     = {Patients with a previous history of anaphylactic reactions to ionic iodinated contrast media were desensitised before a second radiologic examination was performed. The tolerance to the contrast medium was raised by repeated intravenous injections in increasing doses and concentrations. No serious side effects were noted when the examinations with contrast medium was repeated within a few days after the desensitisation. The positive effect of the desensitisation may depend on a successive consumption of complement proteins, probably responsible for the allergic reactions. Therefore, the available amount of complement for some days may be too low for the occurrence of a complement reaction.},
  author       = {Agardh, Carl-David and Arner, B and Ekholm, S and Boijsen, E},
  issn         = {0567-8056},
  language     = {eng},
  number       = {3},
  pages        = {235--239},
  publisher    = {John Wiley & Sons},
  series       = {Acta radiologica: diagnosis},
  title        = {Desensitisation as a means of preventing untoward reactions to ionic contrast media},
  volume       = {24},
  year         = {1983},
}