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Improvement of peripheral nerve function after institution of insulin treatment in diabetes mellitus. A case-control study

Agardh, Carl-David LU ; Rosén, Ingmar LU and Scherstén, Bengt LU (1983) In Acta Medica Scandinavica 213(4). p.283-287
Abstract
The influence of improved diabetic control on peripheral nerve function was studied before and 3-4 months after institution of insulin treatment in 22 diabetics unsatisfactorily controlled by oral hypoglycemic agents. After institution of insulin treatment, diabetic control was improved as demonstrated by decreasing levels of HbA1. There was an overall tendency towards improvement of motor and sensory conduction velocities, however significant only in the upper extremities. There was a tendency towards improved temperature sensitivity in the legs, while no changes occurred in the hands and face. The sensation for vibration did not change. It is concluded that improved diabetic control, even in elderly patients with long-standing diabetes,... (More)
The influence of improved diabetic control on peripheral nerve function was studied before and 3-4 months after institution of insulin treatment in 22 diabetics unsatisfactorily controlled by oral hypoglycemic agents. After institution of insulin treatment, diabetic control was improved as demonstrated by decreasing levels of HbA1. There was an overall tendency towards improvement of motor and sensory conduction velocities, however significant only in the upper extremities. There was a tendency towards improved temperature sensitivity in the legs, while no changes occurred in the hands and face. The sensation for vibration did not change. It is concluded that improved diabetic control, even in elderly patients with long-standing diabetes, is followed by neurophysiological signs of improved peripheral nerve function. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Medica Scandinavica
volume
213
issue
4
pages
283 - 287
publisher
Norstedts
external identifiers
  • pmid:6351551
  • scopus:0020529505
ISSN
0001-6101
language
English
LU publication?
yes
id
53cea0d3-0f3b-4fca-93d3-34c8e88f46b9 (old id 1103069)
date added to LUP
2008-08-13 09:20:25
date last changed
2017-08-06 04:40:52
@article{53cea0d3-0f3b-4fca-93d3-34c8e88f46b9,
  abstract     = {The influence of improved diabetic control on peripheral nerve function was studied before and 3-4 months after institution of insulin treatment in 22 diabetics unsatisfactorily controlled by oral hypoglycemic agents. After institution of insulin treatment, diabetic control was improved as demonstrated by decreasing levels of HbA1. There was an overall tendency towards improvement of motor and sensory conduction velocities, however significant only in the upper extremities. There was a tendency towards improved temperature sensitivity in the legs, while no changes occurred in the hands and face. The sensation for vibration did not change. It is concluded that improved diabetic control, even in elderly patients with long-standing diabetes, is followed by neurophysiological signs of improved peripheral nerve function.},
  author       = {Agardh, Carl-David and Rosén, Ingmar and Scherstén, Bengt},
  issn         = {0001-6101},
  language     = {eng},
  number       = {4},
  pages        = {283--287},
  publisher    = {Norstedts},
  series       = {Acta Medica Scandinavica},
  title        = {Improvement of peripheral nerve function after institution of insulin treatment in diabetes mellitus. A case-control study},
  volume       = {213},
  year         = {1983},
}