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Effect of dietary fibre on blood glucose, plasma immunoreactive insulin, C-peptide and GIP responses in non insulin dependent (type 2) diabetics and controls

Hagander, B; Schersten, B; Asp, N G; Sartor, G; Agardh, Carl-David LU ; Schrezenmeir, J; Kasper, H; Ahren, B and Lundquist, I (1984) In Acta Medica Scandinavica 215(3). p.205-213
Abstract
A high fibre and a low fibre breakfast meal were given to eight non insulin dependent diabetics ( NIDD ), and eight controls. Blood glucose response was monitored continuously for three hours and characterized using a straight line model. After the high fibre meal the rates of increase and decrease in blood glucose concentration were slower both in diabetics and controls than after the low fibre meal. The delay time, however, i.e. the time from meal intake to the start of glucose increase, hypothetically corresponding to gastric emptying time, was the same after both test meals. The postprandial glucose increment calculated as the area under the 0-120 min curve was lower after the high fibre meal in the NIDD , but not in the controls. The... (More)
A high fibre and a low fibre breakfast meal were given to eight non insulin dependent diabetics ( NIDD ), and eight controls. Blood glucose response was monitored continuously for three hours and characterized using a straight line model. After the high fibre meal the rates of increase and decrease in blood glucose concentration were slower both in diabetics and controls than after the low fibre meal. The delay time, however, i.e. the time from meal intake to the start of glucose increase, hypothetically corresponding to gastric emptying time, was the same after both test meals. The postprandial glucose increment calculated as the area under the 0-120 min curve was lower after the high fibre meal in the NIDD , but not in the controls. The two-hour C-peptide and gastric inhibitory polypeptide values were lower for the diabetics after the high fibre breakfast. The results indicate a prolonged carbohydrate digestion and/or absorption after high fibre breakfast. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Medica Scandinavica
volume
215
issue
3
pages
205 - 213
publisher
Norstedts
external identifiers
  • pmid:6328896
  • scopus:0021215351
ISSN
0001-6101
language
English
LU publication?
yes
id
f39df86e-f907-41c2-972e-f50115e42928 (old id 1103228)
date added to LUP
2008-08-12 14:49:05
date last changed
2017-08-20 04:24:16
@article{f39df86e-f907-41c2-972e-f50115e42928,
  abstract     = {A high fibre and a low fibre breakfast meal were given to eight non insulin dependent diabetics ( NIDD ), and eight controls. Blood glucose response was monitored continuously for three hours and characterized using a straight line model. After the high fibre meal the rates of increase and decrease in blood glucose concentration were slower both in diabetics and controls than after the low fibre meal. The delay time, however, i.e. the time from meal intake to the start of glucose increase, hypothetically corresponding to gastric emptying time, was the same after both test meals. The postprandial glucose increment calculated as the area under the 0-120 min curve was lower after the high fibre meal in the NIDD , but not in the controls. The two-hour C-peptide and gastric inhibitory polypeptide values were lower for the diabetics after the high fibre breakfast. The results indicate a prolonged carbohydrate digestion and/or absorption after high fibre breakfast.},
  author       = {Hagander, B and Schersten, B and Asp, N G and Sartor, G and Agardh, Carl-David and Schrezenmeir, J and Kasper, H and Ahren, B and Lundquist, I},
  issn         = {0001-6101},
  language     = {eng},
  number       = {3},
  pages        = {205--213},
  publisher    = {Norstedts},
  series       = {Acta Medica Scandinavica},
  title        = {Effect of dietary fibre on blood glucose, plasma immunoreactive insulin, C-peptide and GIP responses in non insulin dependent (type 2) diabetics and controls},
  volume       = {215},
  year         = {1984},
}