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Immunochemical characterization of a monoclonal anti-Leb blood grouping reagent

Messeter, L; Brodin, T; Chester, Alan LU ; Karlsson, K A; Zopf, D and Lundblad, A (1984) In Vox Sanguinis 46(2). p.66-74
Abstract
A haemagglutinating monoclonal anti-LebL antibody has been obtained from a mouse-mouse hybridoma after immunization with the Leb-active oligosaccharide lacto-N-difucohexaose I, coupled to edestin. Of 13 other antibodies obtained, one was able to agglutinate enzyme-treated erythrocytes of all ABO groups and three more were considered to be anti-LebH haemagglutinins. The remaining nine antibodies did not agglutinate red cells. The specificity of the stronger of the anti-LebL haemagglutinins was examined by studying its binding to a number of glycoconjugates and oligosaccharides.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Vox Sanguinis
volume
46
issue
2
pages
66 - 74
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • pmid:6702144
  • scopus:0021343622
ISSN
1423-0410
language
English
LU publication?
yes
id
683bf348-4997-43ef-9af6-4e10c755cbc8 (old id 1103289)
date added to LUP
2008-08-12 15:58:53
date last changed
2017-02-26 04:05:25
@article{683bf348-4997-43ef-9af6-4e10c755cbc8,
  abstract     = {A haemagglutinating monoclonal anti-LebL antibody has been obtained from a mouse-mouse hybridoma after immunization with the Leb-active oligosaccharide lacto-N-difucohexaose I, coupled to edestin. Of 13 other antibodies obtained, one was able to agglutinate enzyme-treated erythrocytes of all ABO groups and three more were considered to be anti-LebH haemagglutinins. The remaining nine antibodies did not agglutinate red cells. The specificity of the stronger of the anti-LebL haemagglutinins was examined by studying its binding to a number of glycoconjugates and oligosaccharides.},
  author       = {Messeter, L and Brodin, T and Chester, Alan and Karlsson, K A and Zopf, D and Lundblad, A},
  issn         = {1423-0410},
  language     = {eng},
  number       = {2},
  pages        = {66--74},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Vox Sanguinis},
  title        = {Immunochemical characterization of a monoclonal anti-Leb blood grouping reagent},
  volume       = {46},
  year         = {1984},
}