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Immunochemical characterization of a monoclonal anti-Leb blood grouping reagent

Messeter, L ; Brodin, T ; Chester, Alan LU ; Karlsson, K A ; Zopf, D and Lundblad, A (1984) In Vox Sanguinis 46(2). p.66-74
Abstract
A haemagglutinating monoclonal anti-LebL antibody has been obtained from a mouse-mouse hybridoma after immunization with the Leb-active oligosaccharide lacto-N-difucohexaose I, coupled to edestin. Of 13 other antibodies obtained, one was able to agglutinate enzyme-treated erythrocytes of all ABO groups and three more were considered to be anti-LebH haemagglutinins. The remaining nine antibodies did not agglutinate red cells. The specificity of the stronger of the anti-LebL haemagglutinins was examined by studying its binding to a number of glycoconjugates and oligosaccharides.
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Vox Sanguinis
volume
46
issue
2
pages
66 - 74
publisher
Wiley-Blackwell
external identifiers
  • pmid:6702144
  • scopus:0021343622
ISSN
1423-0410
language
English
LU publication?
yes
id
683bf348-4997-43ef-9af6-4e10c755cbc8 (old id 1103289)
date added to LUP
2016-04-01 15:17:03
date last changed
2021-01-03 11:17:16
@article{683bf348-4997-43ef-9af6-4e10c755cbc8,
  abstract     = {{A haemagglutinating monoclonal anti-LebL antibody has been obtained from a mouse-mouse hybridoma after immunization with the Leb-active oligosaccharide lacto-N-difucohexaose I, coupled to edestin. Of 13 other antibodies obtained, one was able to agglutinate enzyme-treated erythrocytes of all ABO groups and three more were considered to be anti-LebH haemagglutinins. The remaining nine antibodies did not agglutinate red cells. The specificity of the stronger of the anti-LebL haemagglutinins was examined by studying its binding to a number of glycoconjugates and oligosaccharides.}},
  author       = {{Messeter, L and Brodin, T and Chester, Alan and Karlsson, K A and Zopf, D and Lundblad, A}},
  issn         = {{1423-0410}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{66--74}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Vox Sanguinis}},
  title        = {{Immunochemical characterization of a monoclonal anti-Leb blood grouping reagent}},
  volume       = {{46}},
  year         = {{1984}},
}