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Distribution of different fibre types in human skeletal muscles. A statistical and computational study of the fibre type arrangement in m. vastus lateralis of young, healthy males

Lexell, Jan LU ; Downham, David and Sjöstrom, Michael (1984) In Journal of the Neurological Sciences 65(3). p.353-365
Abstract
To test whether the arrangement of fibre types in the human muscle (m. vastus lateralis) from clinically healthy and young males can be regarded as random, fascicles at different parts of the muscle and with different fibre type proportions were studied. The randomness of the arrangement of fibre types was assessed by the number of enclosed fibres in a fascicle and, on the basis of a model, tested by simulating muscle cross-sections using a microcomputer. The fibre type proportion was found to vary within a fascicle, so the original model for the test of randomness was modified to allow for different fibre type proportions on the border of the fascicle and internally. The effect of different sizes of the fibre types was also considered.... (More)
To test whether the arrangement of fibre types in the human muscle (m. vastus lateralis) from clinically healthy and young males can be regarded as random, fascicles at different parts of the muscle and with different fibre type proportions were studied. The randomness of the arrangement of fibre types was assessed by the number of enclosed fibres in a fascicle and, on the basis of a model, tested by simulating muscle cross-sections using a microcomputer. The fibre type proportion was found to vary within a fascicle, so the original model for the test of randomness was modified to allow for different fibre type proportions on the border of the fascicle and internally. The effect of different sizes of the fibre types was also considered. The various aspects considered had only a marginal effect on the original model. For this muscle (m. vastus lateralis) the arrangement of fibre types was therefore considered random. Thus, a sample from this muscle, taken from individuals of the same sex and age group, can be tested for non-randomness, as an indication of a successive denervation and reinnervation process. (Less)
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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Diagnosis, computer assisted, Histocytochemistry, Microcomputers, Muscle denervation, Muscles, Needle biopsy, Nerve degeneration, Nerve regeneration
in
Journal of the Neurological Sciences
volume
65
issue
3
pages
353 - 365
publisher
Elsevier
external identifiers
  • pmid:6548511
  • scopus:0021253251
ISSN
1878-5883
DOI
10.1016/0022-510X(84)90098-4
language
English
LU publication?
no
id
023c7210-05e7-41d5-b600-ab1bd80b06dd (old id 1103321)
date added to LUP
2008-08-12 16:20:07
date last changed
2017-08-13 03:43:48
@article{023c7210-05e7-41d5-b600-ab1bd80b06dd,
  abstract     = {To test whether the arrangement of fibre types in the human muscle (m. vastus lateralis) from clinically healthy and young males can be regarded as random, fascicles at different parts of the muscle and with different fibre type proportions were studied. The randomness of the arrangement of fibre types was assessed by the number of enclosed fibres in a fascicle and, on the basis of a model, tested by simulating muscle cross-sections using a microcomputer. The fibre type proportion was found to vary within a fascicle, so the original model for the test of randomness was modified to allow for different fibre type proportions on the border of the fascicle and internally. The effect of different sizes of the fibre types was also considered. The various aspects considered had only a marginal effect on the original model. For this muscle (m. vastus lateralis) the arrangement of fibre types was therefore considered random. Thus, a sample from this muscle, taken from individuals of the same sex and age group, can be tested for non-randomness, as an indication of a successive denervation and reinnervation process.},
  author       = {Lexell, Jan and Downham, David and Sjöstrom, Michael},
  issn         = {1878-5883},
  keyword      = {Diagnosis,computer assisted,Histocytochemistry,Microcomputers,Muscle denervation,Muscles,Needle biopsy,Nerve degeneration,Nerve regeneration},
  language     = {eng},
  number       = {3},
  pages        = {353--365},
  publisher    = {Elsevier},
  series       = {Journal of the Neurological Sciences},
  title        = {Distribution of different fibre types in human skeletal muscles. A statistical and computational study of the fibre type arrangement in m. vastus lateralis of young, healthy males},
  url          = {http://dx.doi.org/10.1016/0022-510X(84)90098-4},
  volume       = {65},
  year         = {1984},
}