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Diabetic control in community care. The use of clinical evaluation and hemoglobin A1

Agardh, Carl-David LU and Scherstén, Bengt LU (1985) In Scandinavian Journal of Primary Health Care 3(1). p.15-18
Abstract
Diabetic control was evaluated in 50 consecutive patients attending a community care centre, either by clinical criteria or by determination of glycosylated hemoglobin (HbA1). Two methods used for the determination of HbA1 were found to give similar results, namely ion exchange chromatography and agar gel electrophoresis. On a group basis, good correlation was observed between HbA1 samples analysed prior to and following the elimination of the labile HbA1 fraction. When comparing three treatment modes (diet alone, hypoglycemic agents or insulin), no significant differences in HbA1 levels were noted. Patients considered to have satisfactory and poor control had significantly higher HbA1 levels than those considered to have good control,... (More)
Diabetic control was evaluated in 50 consecutive patients attending a community care centre, either by clinical criteria or by determination of glycosylated hemoglobin (HbA1). Two methods used for the determination of HbA1 were found to give similar results, namely ion exchange chromatography and agar gel electrophoresis. On a group basis, good correlation was observed between HbA1 samples analysed prior to and following the elimination of the labile HbA1 fraction. When comparing three treatment modes (diet alone, hypoglycemic agents or insulin), no significant differences in HbA1 levels were noted. Patients considered to have satisfactory and poor control had significantly higher HbA1 levels than those considered to have good control, while no differences were seen between those considered to have satisfactory or poor control. It is concluded that the methods described for the determination of HbA1 yield similar results. Clinical evaluation of diabetic control is reliable in patients classified to have good or poor control. However, in many patients who are considered to have satisfactory control, regular determinations of HbA1 provide valuable additional information. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
diabetes mellitus, clinical evaluation, hemoglobin A1
in
Scandinavian Journal of Primary Health Care
volume
3
issue
1
pages
15 - 18
publisher
Taylor & Francis
external identifiers
  • pmid:3903904
  • scopus:0021907620
ISSN
0281-3432
DOI
10.3109/02813438509017731
language
English
LU publication?
yes
id
fc501a17-1365-4a16-acd2-f3cd79783713 (old id 1103410)
date added to LUP
2008-08-11 13:25:22
date last changed
2017-01-01 04:38:56
@article{fc501a17-1365-4a16-acd2-f3cd79783713,
  abstract     = {Diabetic control was evaluated in 50 consecutive patients attending a community care centre, either by clinical criteria or by determination of glycosylated hemoglobin (HbA1). Two methods used for the determination of HbA1 were found to give similar results, namely ion exchange chromatography and agar gel electrophoresis. On a group basis, good correlation was observed between HbA1 samples analysed prior to and following the elimination of the labile HbA1 fraction. When comparing three treatment modes (diet alone, hypoglycemic agents or insulin), no significant differences in HbA1 levels were noted. Patients considered to have satisfactory and poor control had significantly higher HbA1 levels than those considered to have good control, while no differences were seen between those considered to have satisfactory or poor control. It is concluded that the methods described for the determination of HbA1 yield similar results. Clinical evaluation of diabetic control is reliable in patients classified to have good or poor control. However, in many patients who are considered to have satisfactory control, regular determinations of HbA1 provide valuable additional information.},
  author       = {Agardh, Carl-David and Scherstén, Bengt},
  issn         = {0281-3432},
  keyword      = {diabetes mellitus,clinical evaluation,hemoglobin A1},
  language     = {eng},
  number       = {1},
  pages        = {15--18},
  publisher    = {Taylor & Francis},
  series       = {Scandinavian Journal of Primary Health Care},
  title        = {Diabetic control in community care. The use of clinical evaluation and hemoglobin A1},
  url          = {http://dx.doi.org/10.3109/02813438509017731},
  volume       = {3},
  year         = {1985},
}