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Microflora of the gallbladder related to duration of acute cholecystitis

Claesson, B E; Holmlund, D E and Mätzsch, Thomas LU (1986) In Surgery, gynecology & obstetrics 162(6). p.531-535
Abstract
The microflora of the bile and wall of the gallbladder was prospectively investigated in 104 nonselected consecutive patients treated with early cholecystectomy for acute cholecystitis after an average hospital stay of 1.8 days. The chief purpose was to relate the findings of cultures to duration of the illness. Special attention was paid to anaerobic isolation techniques. The cultures yielded 107 strains, representing 36 species, with overall agreement between four different sampling procedures. Aerobic gram-negative rods predominated, followed by streptococci and anaerobes (48, 31 and 15 per cent, respectively). The incidence of positive culture results (always greater than or equal to 10(6) colon forming units per milliliter) was 81 per... (More)
The microflora of the bile and wall of the gallbladder was prospectively investigated in 104 nonselected consecutive patients treated with early cholecystectomy for acute cholecystitis after an average hospital stay of 1.8 days. The chief purpose was to relate the findings of cultures to duration of the illness. Special attention was paid to anaerobic isolation techniques. The cultures yielded 107 strains, representing 36 species, with overall agreement between four different sampling procedures. Aerobic gram-negative rods predominated, followed by streptococci and anaerobes (48, 31 and 15 per cent, respectively). The incidence of positive culture results (always greater than or equal to 10(6) colon forming units per milliliter) was 81 per cent among the patients who underwent operation within two days from the onset of symptoms and 50 to 65 per cent after longer preoperative intervals. The shorter interval was significantly more often associated with growth solely of anaerobes (p = 0.03). Postoperative sepsis was caused by biliary bacteria and not related to preoperative duration of illness. Appropriate perioperative antibiotic coverage significantly reduced sepsis--3 versus 20 per cent (p = 0.05). (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Surgery, gynecology & obstetrics
volume
162
issue
6
pages
531 - 535
publisher
Martin Memorial Foundation
external identifiers
  • pmid:3715685
  • scopus:0022504829
ISSN
0039-6087
language
English
LU publication?
yes
id
4b3c6608-0c2a-4f19-82ef-cbbb8a413452 (old id 1103609)
date added to LUP
2008-08-11 09:46:41
date last changed
2017-01-01 07:22:09
@article{4b3c6608-0c2a-4f19-82ef-cbbb8a413452,
  abstract     = {The microflora of the bile and wall of the gallbladder was prospectively investigated in 104 nonselected consecutive patients treated with early cholecystectomy for acute cholecystitis after an average hospital stay of 1.8 days. The chief purpose was to relate the findings of cultures to duration of the illness. Special attention was paid to anaerobic isolation techniques. The cultures yielded 107 strains, representing 36 species, with overall agreement between four different sampling procedures. Aerobic gram-negative rods predominated, followed by streptococci and anaerobes (48, 31 and 15 per cent, respectively). The incidence of positive culture results (always greater than or equal to 10(6) colon forming units per milliliter) was 81 per cent among the patients who underwent operation within two days from the onset of symptoms and 50 to 65 per cent after longer preoperative intervals. The shorter interval was significantly more often associated with growth solely of anaerobes (p = 0.03). Postoperative sepsis was caused by biliary bacteria and not related to preoperative duration of illness. Appropriate perioperative antibiotic coverage significantly reduced sepsis--3 versus 20 per cent (p = 0.05).},
  author       = {Claesson, B E and Holmlund, D E and Mätzsch, Thomas},
  issn         = {0039-6087},
  language     = {eng},
  number       = {6},
  pages        = {531--535},
  publisher    = {Martin Memorial Foundation},
  series       = {Surgery, gynecology & obstetrics},
  title        = {Microflora of the gallbladder related to duration of acute cholecystitis},
  volume       = {162},
  year         = {1986},
}