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Serum electrolytes and parathyroid hormone concentrations in acute myocardial infarction

Ljunghall, S; Lundin, L; Hvarfner, Andreas LU ; Joborn, H and Wide, L (1986) In Experimental and Clinical Endocrinology 88(1). p.95-100
Abstract
Serum concentrations of calcium, magnesium, potassium and phosphate can be lowered experimentally by adrenaline, which also can stimulate the secretion of parathyroid hormone (PTH). In order to evaluate the possible clinical importance of these mechanisms serial blood samples were drawn during the first three hospital days in 26 patients with acute myocardial infarction (AMI), a condition known to increase plasma catecholamine levels. During the study period there were no consistent significant changes of the serum electrolytes. The serum PTH levels, however, were significantly raised in the AMI patients already on admission and did not normalize during the observation time. The PTH concentrations were unexplained by infarct size,... (More)
Serum concentrations of calcium, magnesium, potassium and phosphate can be lowered experimentally by adrenaline, which also can stimulate the secretion of parathyroid hormone (PTH). In order to evaluate the possible clinical importance of these mechanisms serial blood samples were drawn during the first three hospital days in 26 patients with acute myocardial infarction (AMI), a condition known to increase plasma catecholamine levels. During the study period there were no consistent significant changes of the serum electrolytes. The serum PTH levels, however, were significantly raised in the AMI patients already on admission and did not normalize during the observation time. The PTH concentrations were unexplained by infarct size, concomitant diseases or medication. These findings suggest that PTH could be an independent risk factor for AMI. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Experimental and Clinical Endocrinology
volume
88
issue
1
pages
95 - 100
publisher
Johann Ambrosius Barth
external identifiers
  • pmid:3817007
  • scopus:0022978349
ISSN
0232-7384
language
English
LU publication?
yes
id
fee3012c-5bf4-4527-a4a4-ef624454b7c6 (old id 1103674)
date added to LUP
2008-08-11 10:50:40
date last changed
2017-08-06 04:34:17
@article{fee3012c-5bf4-4527-a4a4-ef624454b7c6,
  abstract     = {Serum concentrations of calcium, magnesium, potassium and phosphate can be lowered experimentally by adrenaline, which also can stimulate the secretion of parathyroid hormone (PTH). In order to evaluate the possible clinical importance of these mechanisms serial blood samples were drawn during the first three hospital days in 26 patients with acute myocardial infarction (AMI), a condition known to increase plasma catecholamine levels. During the study period there were no consistent significant changes of the serum electrolytes. The serum PTH levels, however, were significantly raised in the AMI patients already on admission and did not normalize during the observation time. The PTH concentrations were unexplained by infarct size, concomitant diseases or medication. These findings suggest that PTH could be an independent risk factor for AMI.},
  author       = {Ljunghall, S and Lundin, L and Hvarfner, Andreas and Joborn, H and Wide, L},
  issn         = {0232-7384},
  language     = {eng},
  number       = {1},
  pages        = {95--100},
  publisher    = {Johann Ambrosius Barth},
  series       = {Experimental and Clinical Endocrinology},
  title        = {Serum electrolytes and parathyroid hormone concentrations in acute myocardial infarction},
  volume       = {88},
  year         = {1986},
}