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Early posttraumatic pulmonary platelet trapping and its potentiation by oral pretreatment with alcohol

Thörne, Johan LU ; Blomquist, Sten LU ; Elmér, Olle ; Jönsson, Bo-Anders LU orcid ; Lindahl, Sten and Strand, Sven-Erik LU (1986) In The American Journal of Surgery 151(2). p.216-220
Abstract
Soft tissue trauma is associated with platelet aggregation and sequestration in the lungs. This is believed to be an early step in the later development of adult respiratory distress syndrome. In the present experiment using a new method for in vivo dynamic studies of platelet sequestration, we wanted to evaluate the effect of soft tissue trauma on pulmonary platelet trapping in pigs and the influence of acute alcohol intoxication. The results show that significant pulmonary platelet trapping is registered within minutes of trauma and that alcohol significantly increases platelet sequestration in the lungs. This indicates an increased risk for posttraumatic pulmonary problems in alcohol-intoxicated trauma victims
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
The American Journal of Surgery
volume
151
issue
2
pages
216 - 220
publisher
Elsevier
external identifiers
  • scopus:0022618955
ISSN
1879-1883
DOI
10.1016/0002-9610(86)90073-5
language
English
LU publication?
yes
id
53e02d83-7539-4cbe-ab80-4a5ee16e5d83 (old id 1103725)
date added to LUP
2016-04-01 11:57:39
date last changed
2025-01-02 00:20:59
@article{53e02d83-7539-4cbe-ab80-4a5ee16e5d83,
  abstract     = {{Soft tissue trauma is associated with platelet aggregation and sequestration in the lungs. This is believed to be an early step in the later development of adult respiratory distress syndrome. In the present experiment using a new method for in vivo dynamic studies of platelet sequestration, we wanted to evaluate the effect of soft tissue trauma on pulmonary platelet trapping in pigs and the influence of acute alcohol intoxication. The results show that significant pulmonary platelet trapping is registered within minutes of trauma and that alcohol significantly increases platelet sequestration in the lungs. This indicates an increased risk for posttraumatic pulmonary problems in alcohol-intoxicated trauma victims}},
  author       = {{Thörne, Johan and Blomquist, Sten and Elmér, Olle and Jönsson, Bo-Anders and Lindahl, Sten and Strand, Sven-Erik}},
  issn         = {{1879-1883}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{216--220}},
  publisher    = {{Elsevier}},
  series       = {{The American Journal of Surgery}},
  title        = {{Early posttraumatic pulmonary platelet trapping and its potentiation by oral pretreatment with alcohol}},
  url          = {{http://dx.doi.org/10.1016/0002-9610(86)90073-5}},
  doi          = {{10.1016/0002-9610(86)90073-5}},
  volume       = {{151}},
  year         = {{1986}},
}