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Absence of host-cell influence on binding specificity of herpes simplex virus type 1 induced Fc receptor

Johansson, Hugo LU and Blomberg, J (1987) In Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology 95(3). p.113-116
Abstract
Herpes simplex virus (HSV) infected cells express on their surface a receptor with affinity to the Fc portion of immunoglobulin G (IgG). The influence of the infected host cell on the specificity of the receptor was investigated with radiolabeled human IgG Fc fragment and four animal IgGs (rabbit, dog, cow, and rat) and eight human and animal (primate, rabbit, dog, cow, and rat) fibroblastoid and epithelioid cell lines. Human IgG Fc, rabbit IgG and cow IgG bound to all cell lines infected with HSV type 1 strain F (HSV-1 F), whereas dog IgG and rat IgG did not bind to any of these cells. The same binding pattern was seen when two additional HSV-1 strains infected rabbit epithelial (GMK AH1) cells. The results support the view that the... (More)
Herpes simplex virus (HSV) infected cells express on their surface a receptor with affinity to the Fc portion of immunoglobulin G (IgG). The influence of the infected host cell on the specificity of the receptor was investigated with radiolabeled human IgG Fc fragment and four animal IgGs (rabbit, dog, cow, and rat) and eight human and animal (primate, rabbit, dog, cow, and rat) fibroblastoid and epithelioid cell lines. Human IgG Fc, rabbit IgG and cow IgG bound to all cell lines infected with HSV type 1 strain F (HSV-1 F), whereas dog IgG and rat IgG did not bind to any of these cells. The same binding pattern was seen when two additional HSV-1 strains infected rabbit epithelial (GMK AH1) cells. The results support the view that the specificity of the HSV Fc receptor is mainly under viral control and not primarily influenced by the species of the host cell. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology
volume
95
issue
3
pages
113 - 116
publisher
Munksgaard International Publishers
external identifiers
  • pmid:2820192
  • scopus:0023188680
ISSN
0108-0202
language
English
LU publication?
yes
id
566e4a5b-61c3-456d-8e4b-3311c29ec395 (old id 1103793)
date added to LUP
2008-08-08 12:55:24
date last changed
2017-01-01 06:45:57
@article{566e4a5b-61c3-456d-8e4b-3311c29ec395,
  abstract     = {Herpes simplex virus (HSV) infected cells express on their surface a receptor with affinity to the Fc portion of immunoglobulin G (IgG). The influence of the infected host cell on the specificity of the receptor was investigated with radiolabeled human IgG Fc fragment and four animal IgGs (rabbit, dog, cow, and rat) and eight human and animal (primate, rabbit, dog, cow, and rat) fibroblastoid and epithelioid cell lines. Human IgG Fc, rabbit IgG and cow IgG bound to all cell lines infected with HSV type 1 strain F (HSV-1 F), whereas dog IgG and rat IgG did not bind to any of these cells. The same binding pattern was seen when two additional HSV-1 strains infected rabbit epithelial (GMK AH1) cells. The results support the view that the specificity of the HSV Fc receptor is mainly under viral control and not primarily influenced by the species of the host cell.},
  author       = {Johansson, Hugo and Blomberg, J},
  issn         = {0108-0202},
  language     = {eng},
  number       = {3},
  pages        = {113--116},
  publisher    = {Munksgaard International Publishers},
  series       = {Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology},
  title        = {Absence of host-cell influence on binding specificity of herpes simplex virus type 1 induced Fc receptor},
  volume       = {95},
  year         = {1987},
}