Advanced

Ferruginous bodies and pulmonary fibrosis in dead low to moderately exposed asbestos cement workers: histological examination

Johansson, L G; Albin, Maria LU ; Jakobsson, Kristina LU ; Welinder, Hans LU ; Ranstam, P J and Attewell, Robyn G (1987) In British Journal of Industrial Medicine 44(8). p.550-558
Abstract
Histological slides from the lungs of 89 dead asbestos cement workers have been examined with respect to ferruginous bodies and fibrosis. The results have been compared with individually matched controls with no known exposure to asbestos, and related to asbestos exposure, expressed as duration of exposure and cumulative asbestos dose, and smoking habits. The asbestos cement workers studied had been employed for on average 15 years, with a mean cumulative dose of 26 fibre-years per ml (f-y/ml). Clear dose-response relations between exposure (duration of exposure and cumulative asbestos dose) and level of ferruginous bodies were found. An association was evident already at a low cumulative dose (1-10 f-y/ml). Fibrosis was more common and... (More)
Histological slides from the lungs of 89 dead asbestos cement workers have been examined with respect to ferruginous bodies and fibrosis. The results have been compared with individually matched controls with no known exposure to asbestos, and related to asbestos exposure, expressed as duration of exposure and cumulative asbestos dose, and smoking habits. The asbestos cement workers studied had been employed for on average 15 years, with a mean cumulative dose of 26 fibre-years per ml (f-y/ml). Clear dose-response relations between exposure (duration of exposure and cumulative asbestos dose) and level of ferruginous bodies were found. An association was evident already at a low cumulative dose (1-10 f-y/ml). Fibrosis was more common and more pronounced among the exposed workers than among controls. An association between ferruginous bodies and fibrosis was also found. Among the controls, but not among exposed workers, there was an association between smoking history and fibrosis. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
British Journal of Industrial Medicine
volume
44
issue
8
pages
550 - 558
publisher
BMJ Publishing Group
external identifiers
  • pmid:3651354
  • scopus:0023255911
ISSN
0007-1072
language
English
LU publication?
yes
id
7b3239c2-bedb-42d6-a8b7-5ba5339dfcda (old id 1103802)
alternative location
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1007874&blobtype=pdf
date added to LUP
2008-08-08 13:02:58
date last changed
2017-01-01 07:15:54
@article{7b3239c2-bedb-42d6-a8b7-5ba5339dfcda,
  abstract     = {Histological slides from the lungs of 89 dead asbestos cement workers have been examined with respect to ferruginous bodies and fibrosis. The results have been compared with individually matched controls with no known exposure to asbestos, and related to asbestos exposure, expressed as duration of exposure and cumulative asbestos dose, and smoking habits. The asbestos cement workers studied had been employed for on average 15 years, with a mean cumulative dose of 26 fibre-years per ml (f-y/ml). Clear dose-response relations between exposure (duration of exposure and cumulative asbestos dose) and level of ferruginous bodies were found. An association was evident already at a low cumulative dose (1-10 f-y/ml). Fibrosis was more common and more pronounced among the exposed workers than among controls. An association between ferruginous bodies and fibrosis was also found. Among the controls, but not among exposed workers, there was an association between smoking history and fibrosis.},
  author       = {Johansson, L G and Albin, Maria and Jakobsson, Kristina and Welinder, Hans and Ranstam, P J and Attewell, Robyn G},
  issn         = {0007-1072},
  language     = {eng},
  number       = {8},
  pages        = {550--558},
  publisher    = {BMJ Publishing Group},
  series       = {British Journal of Industrial Medicine},
  title        = {Ferruginous bodies and pulmonary fibrosis in dead low to moderately exposed asbestos cement workers: histological examination},
  volume       = {44},
  year         = {1987},
}