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Measurement of lung density by x-ray computed tomography. Relation to lung mechanics in workers exposed to asbestos cement

Wollmer, Per LU ; Jakobsson, Kristina LU ; Albin, Maria LU ; Albrechtsson, Ulf LU ; Brauer, Kerstin LU ; Eriksson, Leif; Jonson, Björn LU ; Skerfving, Staffan LU and Tylen, Ulf (1987) In Chest 91(6). p.865-869
Abstract
We measured lung density by means of x-ray computed tomography and lung mechanics in 33 workers exposed to asbestos cement and in 39 normal subjects. The exposed group showed evidence of lung fibrosis with reduced static lung volumes and lung compliance, although only three subjects had signs of interstitial fibrosis at standard chest radiography. Lung density was significantly increased in the exposed workers compared to control subjects, with greater differences between nonsmokers than between smokers. Lung density correlated inversely with static lung volumes. There was no appreciable difference in the regional distribution of lung density between exposed workers and control subjects. We conclude that lung density is often increased in... (More)
We measured lung density by means of x-ray computed tomography and lung mechanics in 33 workers exposed to asbestos cement and in 39 normal subjects. The exposed group showed evidence of lung fibrosis with reduced static lung volumes and lung compliance, although only three subjects had signs of interstitial fibrosis at standard chest radiography. Lung density was significantly increased in the exposed workers compared to control subjects, with greater differences between nonsmokers than between smokers. Lung density correlated inversely with static lung volumes. There was no appreciable difference in the regional distribution of lung density between exposed workers and control subjects. We conclude that lung density is often increased in workers with mild asbestosis, even in the presence of a normal chest radiograph. Measurement of lung density may be of value in the evaluation of asbestos-exposed workers for assessment of the extent of parenchymal disease. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Chest
volume
91
issue
6
pages
865 - 869
publisher
American College of Chest Physicians
external identifiers
  • pmid:3646942
  • scopus:0023359297
ISSN
1931-3543
DOI
10.1378/chest.91.6.865
language
English
LU publication?
yes
id
90ea738e-bc2a-49a9-9745-9b32b2432f4a (old id 1103815)
date added to LUP
2008-08-08 13:18:23
date last changed
2017-01-01 07:20:47
@article{90ea738e-bc2a-49a9-9745-9b32b2432f4a,
  abstract     = {We measured lung density by means of x-ray computed tomography and lung mechanics in 33 workers exposed to asbestos cement and in 39 normal subjects. The exposed group showed evidence of lung fibrosis with reduced static lung volumes and lung compliance, although only three subjects had signs of interstitial fibrosis at standard chest radiography. Lung density was significantly increased in the exposed workers compared to control subjects, with greater differences between nonsmokers than between smokers. Lung density correlated inversely with static lung volumes. There was no appreciable difference in the regional distribution of lung density between exposed workers and control subjects. We conclude that lung density is often increased in workers with mild asbestosis, even in the presence of a normal chest radiograph. Measurement of lung density may be of value in the evaluation of asbestos-exposed workers for assessment of the extent of parenchymal disease.},
  author       = {Wollmer, Per and Jakobsson, Kristina and Albin, Maria and Albrechtsson, Ulf and Brauer, Kerstin and Eriksson, Leif and Jonson, Björn and Skerfving, Staffan and Tylen, Ulf},
  issn         = {1931-3543},
  language     = {eng},
  number       = {6},
  pages        = {865--869},
  publisher    = {American College of Chest Physicians},
  series       = {Chest},
  title        = {Measurement of lung density by x-ray computed tomography. Relation to lung mechanics in workers exposed to asbestos cement},
  url          = {http://dx.doi.org/10.1378/chest.91.6.865},
  volume       = {91},
  year         = {1987},
}