Advanced

Clinical studies of calcium metabolism in essential hypertension

Ljunghall, S; Hvarfner, Andreas LU and Lind, L (1987) In European Heart Journal 8(Suppl. B). p.37-44
Abstract
Many factors can ultimately lead to an increased blood pressure and it is a generally accepted view that an increase in the active tension of arterioles reflects an increase of the free calcium concentration in the cytosol of the vascular smooth muscle cells. Only recently, however, has the possibility been considered that blood pressure regulation could be influenced by calcium homeostasis. A background for these studies has been provided by the epidemiological observations which link hypertension to a low dietary intake of calcium as well as experimental studies in animals, mostly rats, which have demonstrated that various disturbances of calcium metabolism are related to a raised blood pressure. This review is focused on clinical... (More)
Many factors can ultimately lead to an increased blood pressure and it is a generally accepted view that an increase in the active tension of arterioles reflects an increase of the free calcium concentration in the cytosol of the vascular smooth muscle cells. Only recently, however, has the possibility been considered that blood pressure regulation could be influenced by calcium homeostasis. A background for these studies has been provided by the epidemiological observations which link hypertension to a low dietary intake of calcium as well as experimental studies in animals, mostly rats, which have demonstrated that various disturbances of calcium metabolism are related to a raised blood pressure. This review is focused on clinical studies of a possible association between systemic calcium metabolism and the regulation of blood pressure. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Heart Journal
volume
8
issue
Suppl. B
pages
37 - 44
publisher
Oxford University Press
external identifiers
  • pmid:3301355
  • scopus:0023258370
ISSN
1522-9645
language
English
LU publication?
yes
id
826b5ba5-b70a-4a82-b0ef-228c33ebaca8 (old id 1103975)
date added to LUP
2008-08-08 17:15:09
date last changed
2017-08-06 04:43:14
@article{826b5ba5-b70a-4a82-b0ef-228c33ebaca8,
  abstract     = {Many factors can ultimately lead to an increased blood pressure and it is a generally accepted view that an increase in the active tension of arterioles reflects an increase of the free calcium concentration in the cytosol of the vascular smooth muscle cells. Only recently, however, has the possibility been considered that blood pressure regulation could be influenced by calcium homeostasis. A background for these studies has been provided by the epidemiological observations which link hypertension to a low dietary intake of calcium as well as experimental studies in animals, mostly rats, which have demonstrated that various disturbances of calcium metabolism are related to a raised blood pressure. This review is focused on clinical studies of a possible association between systemic calcium metabolism and the regulation of blood pressure.},
  author       = {Ljunghall, S and Hvarfner, Andreas and Lind, L},
  issn         = {1522-9645},
  language     = {eng},
  number       = {Suppl. B},
  pages        = {37--44},
  publisher    = {Oxford University Press},
  series       = {European Heart Journal},
  title        = {Clinical studies of calcium metabolism in essential hypertension},
  volume       = {8},
  year         = {1987},
}