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Morphological findings in placentae of insulin-dependent diabetic patients treated with continuous subcutaneous insulin infusion (CSII)

Laurini, Ricardo LU ; Visser, G H; van Ballegooie, E and Schoots, C J (1987) In Placenta 8(2). p.153-165
Abstract
Twenty-one placentae from type I (insulin-dependent) pregnant diabetic patients, treated with continuous subcutaneous insulin infusion (CSII), were studied morphologically. Despite a near-optimal blood glucose control the placental changes were identical to those previously reported in diabetic pregnancy. The most frequently observed lesion was that of relative placental immaturity; this, when extensive, was related to antenatal fetal asphyxia. These data indicate that near normoglycaemia, achieved with CSII, does not modify the morphological expression of the disease in the placenta. Furthermore, it highlights the importance of placental development in the context of diabetic pregnancy.
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author
publishing date
type
Contribution to journal
publication status
published
subject
in
Placenta
volume
8
issue
2
pages
153 - 165
publisher
W B Saunders
external identifiers
  • pmid:3615374
  • scopus:0023256029
ISSN
1532-3102
DOI
10.1016/0143-4004(87)90018-X
language
English
LU publication?
no
id
2cf0c560-d232-49cc-8267-664d72046e42 (old id 1104015)
date added to LUP
2008-08-08 17:45:19
date last changed
2017-09-17 04:49:34
@article{2cf0c560-d232-49cc-8267-664d72046e42,
  abstract     = {Twenty-one placentae from type I (insulin-dependent) pregnant diabetic patients, treated with continuous subcutaneous insulin infusion (CSII), were studied morphologically. Despite a near-optimal blood glucose control the placental changes were identical to those previously reported in diabetic pregnancy. The most frequently observed lesion was that of relative placental immaturity; this, when extensive, was related to antenatal fetal asphyxia. These data indicate that near normoglycaemia, achieved with CSII, does not modify the morphological expression of the disease in the placenta. Furthermore, it highlights the importance of placental development in the context of diabetic pregnancy.},
  author       = {Laurini, Ricardo and Visser, G H and van Ballegooie, E and Schoots, C J},
  issn         = {1532-3102},
  language     = {eng},
  number       = {2},
  pages        = {153--165},
  publisher    = {W B Saunders},
  series       = {Placenta},
  title        = {Morphological findings in placentae of insulin-dependent diabetic patients treated with continuous subcutaneous insulin infusion (CSII)},
  url          = {http://dx.doi.org/10.1016/0143-4004(87)90018-X},
  volume       = {8},
  year         = {1987},
}