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Normal visual fields as assessed by computerized static threshold perimetry in patients with untreated primary hypothyroidism

Hallengren, Bengt LU ; Manhem, P; Bramnert, Margareta LU ; Redlund-Johnell, Inga LU and Heijl, Anders LU (1989) In Acta Endocrinologica 121(4). p.495-500
Abstract
In this prospective study, 25 consecutive patients with untreated primary hypothyroidism were tested with a highly sensitive perimetric technique, since a high prevalence of visual field defects has been described in this condition. All patients had clinical hypothyroidism, a serum TSH value greater than 20 mU/l (reference range 0.4-4.0) and decreased/low normal serum total T4 concentration. Visual fields were tested with fully automated threshold-measuring computerized perimetry of the central 30 degrees field. Interpretation of fields included computer-assisted analysis provided by a perimetric statistical programme package. In 23 patients, conventional inspection and computer-assisted analysis showed no visual field defects. Two... (More)
In this prospective study, 25 consecutive patients with untreated primary hypothyroidism were tested with a highly sensitive perimetric technique, since a high prevalence of visual field defects has been described in this condition. All patients had clinical hypothyroidism, a serum TSH value greater than 20 mU/l (reference range 0.4-4.0) and decreased/low normal serum total T4 concentration. Visual fields were tested with fully automated threshold-measuring computerized perimetry of the central 30 degrees field. Interpretation of fields included computer-assisted analysis provided by a perimetric statistical programme package. In 23 patients, conventional inspection and computer-assisted analysis showed no visual field defects. Two patients were excluded from the latter analysis: one patient who did not respond adequately at computerized perimetry and in whom manual field tests were entirely normal: one patient who had low sensitivity values in the uppermost parts of both visual fields owing to markedly swollen upper eye lids. In conclusion, although pituitary hyperplasia has been well documented in primary hypothyroidism, the present prospective study clearly indicates that visual field defects are not a common finding in patients with this disease. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
in
Acta Endocrinologica
volume
121
issue
4
pages
495 - 500
publisher
Scandinavian University Press
external identifiers
  • pmid:2800923
  • scopus:0024374044
ISSN
0001-5598
language
English
LU publication?
yes
id
e30c105a-d588-4217-b62a-1eb3a04e0ab4 (old id 1104546)
date added to LUP
2008-08-06 10:44:44
date last changed
2017-01-01 07:18:56
@article{e30c105a-d588-4217-b62a-1eb3a04e0ab4,
  abstract     = {In this prospective study, 25 consecutive patients with untreated primary hypothyroidism were tested with a highly sensitive perimetric technique, since a high prevalence of visual field defects has been described in this condition. All patients had clinical hypothyroidism, a serum TSH value greater than 20 mU/l (reference range 0.4-4.0) and decreased/low normal serum total T4 concentration. Visual fields were tested with fully automated threshold-measuring computerized perimetry of the central 30 degrees field. Interpretation of fields included computer-assisted analysis provided by a perimetric statistical programme package. In 23 patients, conventional inspection and computer-assisted analysis showed no visual field defects. Two patients were excluded from the latter analysis: one patient who did not respond adequately at computerized perimetry and in whom manual field tests were entirely normal: one patient who had low sensitivity values in the uppermost parts of both visual fields owing to markedly swollen upper eye lids. In conclusion, although pituitary hyperplasia has been well documented in primary hypothyroidism, the present prospective study clearly indicates that visual field defects are not a common finding in patients with this disease.},
  author       = {Hallengren, Bengt and Manhem, P and Bramnert, Margareta and Redlund-Johnell, Inga and Heijl, Anders},
  issn         = {0001-5598},
  language     = {eng},
  number       = {4},
  pages        = {495--500},
  publisher    = {Scandinavian University Press},
  series       = {Acta Endocrinologica},
  title        = {Normal visual fields as assessed by computerized static threshold perimetry in patients with untreated primary hypothyroidism},
  volume       = {121},
  year         = {1989},
}