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Putative risk factors associated with retinopathy in patients with diabetes diagnosed at or after 30 years of age

Agardh, Elisabet LU ; Torffvit, Ole LU and Agardh, Carl-David LU (1989) In Diabetic Medicine 6(8). p.724-727
Abstract
In a cross-sectional study of diabetic patients diagnosed at or after 30 years, and with different stages of retinopathy, factors such as duration of diabetes, treatment mode, metabolic control, blood pressure, and clinical signs of nephropathy were examined. The different stages of retinopathy used were absence of retinopathy, simplex, and severe retinopathy. Patients with simplex and severe retinopathy were older than those without retinopathy (p less than 0.001, and p less than 0.01, respectively). They also had a longer duration of diabetes (p less than 0.001), and were more often treated with insulin (p less than 0.001) and in larger doses (p less than 0.001). Their glycosylated haemoglobin levels were higher (p less than 0.01). Their... (More)
In a cross-sectional study of diabetic patients diagnosed at or after 30 years, and with different stages of retinopathy, factors such as duration of diabetes, treatment mode, metabolic control, blood pressure, and clinical signs of nephropathy were examined. The different stages of retinopathy used were absence of retinopathy, simplex, and severe retinopathy. Patients with simplex and severe retinopathy were older than those without retinopathy (p less than 0.001, and p less than 0.01, respectively). They also had a longer duration of diabetes (p less than 0.001), and were more often treated with insulin (p less than 0.001) and in larger doses (p less than 0.001). Their glycosylated haemoglobin levels were higher (p less than 0.01). Their systolic blood pressure was higher (p less than 0.01), but the diastolic blood pressure did not differ, and the number of patients treated for hypertension was similar in all groups. Albumin clearance was higher (p less than 0.01 and p less than 0.001), as were urinary albumin levels (p less than 0.001). The only variables that distinguished patients with simplex from those with severe retinopathy were albumin clearance (p less than 0.01) and urinary albumin levels (p less than 0.05). (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diabetic Medicine
volume
6
issue
8
pages
724 - 727
publisher
Wiley-Blackwell
external identifiers
  • pmid:2532109
  • scopus:0024427820
ISSN
1464-5491
language
English
LU publication?
yes
id
2901e64a-bfa8-4d64-a717-0fdc4e9f102c (old id 1104557)
date added to LUP
2008-08-06 10:51:13
date last changed
2017-01-01 07:24:23
@article{2901e64a-bfa8-4d64-a717-0fdc4e9f102c,
  abstract     = {In a cross-sectional study of diabetic patients diagnosed at or after 30 years, and with different stages of retinopathy, factors such as duration of diabetes, treatment mode, metabolic control, blood pressure, and clinical signs of nephropathy were examined. The different stages of retinopathy used were absence of retinopathy, simplex, and severe retinopathy. Patients with simplex and severe retinopathy were older than those without retinopathy (p less than 0.001, and p less than 0.01, respectively). They also had a longer duration of diabetes (p less than 0.001), and were more often treated with insulin (p less than 0.001) and in larger doses (p less than 0.001). Their glycosylated haemoglobin levels were higher (p less than 0.01). Their systolic blood pressure was higher (p less than 0.01), but the diastolic blood pressure did not differ, and the number of patients treated for hypertension was similar in all groups. Albumin clearance was higher (p less than 0.01 and p less than 0.001), as were urinary albumin levels (p less than 0.001). The only variables that distinguished patients with simplex from those with severe retinopathy were albumin clearance (p less than 0.01) and urinary albumin levels (p less than 0.05).},
  author       = {Agardh, Elisabet and Torffvit, Ole and Agardh, Carl-David},
  issn         = {1464-5491},
  language     = {eng},
  number       = {8},
  pages        = {724--727},
  publisher    = {Wiley-Blackwell},
  series       = {Diabetic Medicine},
  title        = {Putative risk factors associated with retinopathy in patients with diabetes diagnosed at or after 30 years of age},
  volume       = {6},
  year         = {1989},
}