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Myometrial norepinephrine in human pregnancy. Elevated levels in various disorders leading to cesarean section

Rydhstrom, H; Walles, B and Owman, Christer LU (1989) In Journal of Reproductive Medicine 34(11). p.901-904
Abstract
Myometrial norepinephrine was measured consecutively with high-performance liquid chromatography in women who delivered by cesarean section. The previously recorded marked reduction in tissue norepinephrine at the end of normal pregnancy was confirmed. When cesarean section was performed because of abruptio placentae/hemorrhage, impending asphyxia, dystocia or preeclampsia, the norepinephrine concentrations were six to ten times higher than in normal pregnancy. When an emergency cesarean section was carried out for premature breech presentation, transverse position of the fetus or prolapse of the umbilical cord (following an otherwise-normal pregnancy), the reduced norepinephrine values were not significantly different from those measured... (More)
Myometrial norepinephrine was measured consecutively with high-performance liquid chromatography in women who delivered by cesarean section. The previously recorded marked reduction in tissue norepinephrine at the end of normal pregnancy was confirmed. When cesarean section was performed because of abruptio placentae/hemorrhage, impending asphyxia, dystocia or preeclampsia, the norepinephrine concentrations were six to ten times higher than in normal pregnancy. When an emergency cesarean section was carried out for premature breech presentation, transverse position of the fetus or prolapse of the umbilical cord (following an otherwise-normal pregnancy), the reduced norepinephrine values were not significantly different from those measured in a control group of women who underwent elective cesarean section. It is possible that the abnormally elevated levels of myometrial norepinephrine are part of the primary pathophysiologic condition associated with sympathetic overactivity, resulting in disturbed myometrial circulation and/or motor activity. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Reproductive Medicine
volume
34
issue
11
pages
901 - 904
publisher
Journal of Reproductive Medicine, Inc.
external identifiers
  • pmid:2585392
  • scopus:0024317025
ISSN
0024-7758
language
English
LU publication?
yes
id
cff343bb-fdbb-4869-b91b-7dc9bd06d233 (old id 1104655)
date added to LUP
2008-08-06 12:35:21
date last changed
2017-07-30 04:41:20
@article{cff343bb-fdbb-4869-b91b-7dc9bd06d233,
  abstract     = {Myometrial norepinephrine was measured consecutively with high-performance liquid chromatography in women who delivered by cesarean section. The previously recorded marked reduction in tissue norepinephrine at the end of normal pregnancy was confirmed. When cesarean section was performed because of abruptio placentae/hemorrhage, impending asphyxia, dystocia or preeclampsia, the norepinephrine concentrations were six to ten times higher than in normal pregnancy. When an emergency cesarean section was carried out for premature breech presentation, transverse position of the fetus or prolapse of the umbilical cord (following an otherwise-normal pregnancy), the reduced norepinephrine values were not significantly different from those measured in a control group of women who underwent elective cesarean section. It is possible that the abnormally elevated levels of myometrial norepinephrine are part of the primary pathophysiologic condition associated with sympathetic overactivity, resulting in disturbed myometrial circulation and/or motor activity.},
  author       = {Rydhstrom, H and Walles, B and Owman, Christer},
  issn         = {0024-7758},
  language     = {eng},
  number       = {11},
  pages        = {901--904},
  publisher    = {Journal of Reproductive Medicine, Inc.},
  series       = {Journal of Reproductive Medicine},
  title        = {Myometrial norepinephrine in human pregnancy. Elevated levels in various disorders leading to cesarean section},
  volume       = {34},
  year         = {1989},
}