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Binding of IgA and/or IgG is a common property among clinical isolates of group A streptococci

Lindahl, Gunnar LU and Stenberg, Lars LU (1990) In Epidemiology and Infection 105(1). p.87-93
Abstract
Certain strains of group A streptococci are known to bind IgA and/or IgG via a cell surface receptor, which may act as a virulence factor. The distribution of such receptors among routine clinical isolates was studied, using a total of 225 strains and an assay based on the binding of radiolabelled immunoglobulins. Among 194 throat strains isolated during three different time periods in two different geographical areas of Sweden, 82% showed significant binding of IgA and/or IgG. Studies on 31 septicaemia strains, isolated over a period of more than 8 years, showed binding for 84% of the isolates. The binding strains were of several different T-types and could be subdivided into two groups, those binding both IgA and IgG and those binding... (More)
Certain strains of group A streptococci are known to bind IgA and/or IgG via a cell surface receptor, which may act as a virulence factor. The distribution of such receptors among routine clinical isolates was studied, using a total of 225 strains and an assay based on the binding of radiolabelled immunoglobulins. Among 194 throat strains isolated during three different time periods in two different geographical areas of Sweden, 82% showed significant binding of IgA and/or IgG. Studies on 31 septicaemia strains, isolated over a period of more than 8 years, showed binding for 84% of the isolates. The binding strains were of several different T-types and could be subdivided into two groups, those binding both IgA and IgG and those binding IgG only. These data show that binding of IgA and/or IgG is a very common property among clinical isolates of group A streptococci. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Epidemiology and Infection
volume
105
issue
1
pages
87 - 93
publisher
Cambridge University Press
external identifiers
  • pmid:2143481
  • scopus:0025151233
ISSN
0950-2688
language
English
LU publication?
yes
id
dd68c4e1-c319-4f20-a58b-0a6bd4c4ea6a (old id 1105120)
date added to LUP
2008-08-04 17:07:00
date last changed
2017-08-06 03:44:39
@article{dd68c4e1-c319-4f20-a58b-0a6bd4c4ea6a,
  abstract     = {Certain strains of group A streptococci are known to bind IgA and/or IgG via a cell surface receptor, which may act as a virulence factor. The distribution of such receptors among routine clinical isolates was studied, using a total of 225 strains and an assay based on the binding of radiolabelled immunoglobulins. Among 194 throat strains isolated during three different time periods in two different geographical areas of Sweden, 82% showed significant binding of IgA and/or IgG. Studies on 31 septicaemia strains, isolated over a period of more than 8 years, showed binding for 84% of the isolates. The binding strains were of several different T-types and could be subdivided into two groups, those binding both IgA and IgG and those binding IgG only. These data show that binding of IgA and/or IgG is a very common property among clinical isolates of group A streptococci.},
  author       = {Lindahl, Gunnar and Stenberg, Lars},
  issn         = {0950-2688},
  language     = {eng},
  number       = {1},
  pages        = {87--93},
  publisher    = {Cambridge University Press},
  series       = {Epidemiology and Infection},
  title        = {Binding of IgA and/or IgG is a common property among clinical isolates of group A streptococci},
  volume       = {105},
  year         = {1990},
}