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Right-left correlation in guinea pig ears after noise exposure

Grenner, Jan LU ; Nilsson, Per and Katbamna, Bharti (1990) In Acta Oto-Laryngologica 109(1-2). p.41-48
Abstract
In order to investigate whether experimental material consisting of noise-exposed animals should be regarded as 'ears' or 'animals', a comparison was made between the permanent threshold shifts in the right and left ears in 53 groups of noise-exposed guinea-pigs, with 5 animals in each group. The action potential (N1) thresholds were measured at fourteen frequencies in both ears. In the noise-exposed animals, the threshold elevations were up to 40 dB. The average right-left correlation coefficient within each group was about 0.79, regardless of noise energy. The degree of correlation was significantly greater after impact noise than after continuous noise. As a consequence of the high right-left correlation, the informative value of... (More)
In order to investigate whether experimental material consisting of noise-exposed animals should be regarded as 'ears' or 'animals', a comparison was made between the permanent threshold shifts in the right and left ears in 53 groups of noise-exposed guinea-pigs, with 5 animals in each group. The action potential (N1) thresholds were measured at fourteen frequencies in both ears. In the noise-exposed animals, the threshold elevations were up to 40 dB. The average right-left correlation coefficient within each group was about 0.79, regardless of noise energy. The degree of correlation was significantly greater after impact noise than after continuous noise. As a consequence of the high right-left correlation, the informative value of measuring a second ear in the same animal was, in our experiments, only 11% of that of the first one. No correlation could be found between the degree of skin pigmentation and the threshold elevation. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
acoustic trauma, interaural asymmetry, melanin
in
Acta Oto-Laryngologica
volume
109
issue
1-2
pages
41 - 48
publisher
Taylor & Francis
external identifiers
  • pmid:2309558
  • scopus:0025017691
ISSN
1651-2251
DOI
10.3109/00016489009107413
language
English
LU publication?
yes
id
3ccbc4f2-b817-4e81-9172-5e94fbd3d649 (old id 1105181)
date added to LUP
2008-08-05 10:23:19
date last changed
2017-08-06 04:31:16
@article{3ccbc4f2-b817-4e81-9172-5e94fbd3d649,
  abstract     = {In order to investigate whether experimental material consisting of noise-exposed animals should be regarded as 'ears' or 'animals', a comparison was made between the permanent threshold shifts in the right and left ears in 53 groups of noise-exposed guinea-pigs, with 5 animals in each group. The action potential (N1) thresholds were measured at fourteen frequencies in both ears. In the noise-exposed animals, the threshold elevations were up to 40 dB. The average right-left correlation coefficient within each group was about 0.79, regardless of noise energy. The degree of correlation was significantly greater after impact noise than after continuous noise. As a consequence of the high right-left correlation, the informative value of measuring a second ear in the same animal was, in our experiments, only 11% of that of the first one. No correlation could be found between the degree of skin pigmentation and the threshold elevation.},
  author       = {Grenner, Jan and Nilsson, Per and Katbamna, Bharti},
  issn         = {1651-2251},
  keyword      = {acoustic trauma,interaural asymmetry,melanin},
  language     = {eng},
  number       = {1-2},
  pages        = {41--48},
  publisher    = {Taylor & Francis},
  series       = {Acta Oto-Laryngologica},
  title        = {Right-left correlation in guinea pig ears after noise exposure},
  url          = {http://dx.doi.org/10.3109/00016489009107413},
  volume       = {109},
  year         = {1990},
}