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The diagnosis of bacteriuria during pregnancy

Lorentzon, Siri; Hovelius, Birgitta LU ; Miörner, Håkan LU ; Tendler, Maria and Åberg, Anders E LU (1990) In Scandinavian Journal of Primary Health Care 8(2). p.81-83
Abstract
Three diagnostic tests, Nitur, Urobact, and Uricult, were evaluated in the detection of bacteriuria in 865 pregnant women. As reference method agar culture was performed. Heavy growth (greater than 10(5) CFU/ml) of urinary tract bacteria was considered a true positive result and demonstrated in 58 (6.7%) of the women, 14 of whom had gram-negative rods. The sensitivity of the nitrite test was extremely low (0.13). The test gave negative results in eight of 17 specimens yielding heavy growth of Escherichia coli or Proteus mirabilis. Although the Urobact test was highly sensitive as regards gram-negative infection, it had an unacceptably low (0.27) predictive value in positive tests. The sensitivity of the Uricult test was low (0.35) in this... (More)
Three diagnostic tests, Nitur, Urobact, and Uricult, were evaluated in the detection of bacteriuria in 865 pregnant women. As reference method agar culture was performed. Heavy growth (greater than 10(5) CFU/ml) of urinary tract bacteria was considered a true positive result and demonstrated in 58 (6.7%) of the women, 14 of whom had gram-negative rods. The sensitivity of the nitrite test was extremely low (0.13). The test gave negative results in eight of 17 specimens yielding heavy growth of Escherichia coli or Proteus mirabilis. Although the Urobact test was highly sensitive as regards gram-negative infection, it had an unacceptably low (0.27) predictive value in positive tests. The sensitivity of the Uricult test was low (0.35) in this study. The predictive value (0.50) of a positive test result may be acceptable, since just over half of the false positive results were explainable by moderate growth of urinary tract pathogens (10(4)-10(5) CFU/ml). It is argued that semi-quantitative urine culture may be preferable to the rapid diagnostic methods studied for the screening of bacteriuria in pregnant women. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
kit, bacteriuria, pregnancy, screening
in
Scandinavian Journal of Primary Health Care
volume
8
issue
2
pages
81 - 83
publisher
Taylor & Francis
external identifiers
  • pmid:2218158
  • scopus:0025157910
ISSN
0281-3432
DOI
10.3109/02813439008994935
language
English
LU publication?
yes
id
722f57f8-3bce-47dc-a888-68c1035b78b7 (old id 1105433)
date added to LUP
2008-08-05 14:56:10
date last changed
2017-02-12 03:32:06
@article{722f57f8-3bce-47dc-a888-68c1035b78b7,
  abstract     = {Three diagnostic tests, Nitur, Urobact, and Uricult, were evaluated in the detection of bacteriuria in 865 pregnant women. As reference method agar culture was performed. Heavy growth (greater than 10(5) CFU/ml) of urinary tract bacteria was considered a true positive result and demonstrated in 58 (6.7%) of the women, 14 of whom had gram-negative rods. The sensitivity of the nitrite test was extremely low (0.13). The test gave negative results in eight of 17 specimens yielding heavy growth of Escherichia coli or Proteus mirabilis. Although the Urobact test was highly sensitive as regards gram-negative infection, it had an unacceptably low (0.27) predictive value in positive tests. The sensitivity of the Uricult test was low (0.35) in this study. The predictive value (0.50) of a positive test result may be acceptable, since just over half of the false positive results were explainable by moderate growth of urinary tract pathogens (10(4)-10(5) CFU/ml). It is argued that semi-quantitative urine culture may be preferable to the rapid diagnostic methods studied for the screening of bacteriuria in pregnant women.},
  author       = {Lorentzon, Siri and Hovelius, Birgitta and Miörner, Håkan and Tendler, Maria and Åberg, Anders E},
  issn         = {0281-3432},
  keyword      = {kit,bacteriuria,pregnancy,screening},
  language     = {eng},
  number       = {2},
  pages        = {81--83},
  publisher    = {Taylor & Francis},
  series       = {Scandinavian Journal of Primary Health Care},
  title        = {The diagnosis of bacteriuria during pregnancy},
  url          = {http://dx.doi.org/10.3109/02813439008994935},
  volume       = {8},
  year         = {1990},
}