Advanced

In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements

Marchesini, Renato; Brambilla, Marco; Clemente, Claudio; Maniezzo, Massimo; Sichirollo, Adele E; Testori, Alessandro; Venturoli, Daniele LU and Cascinelli, Natale (1991) In Photochemistry and Photobiology 53(1). p.77-84
Abstract
Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of the different lesions manifest dissimilar patterns, particularly in the near IR region. Comparison of reflectance of nevi with that of malignant melanomas results in a highly significant difference (P less than 10(-6)) between the two samples. Though interpretation of the spectra remains difficult as a result of the complexity of the optical processes of scattering and absorption, our results suggest that a... (More)
Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of the different lesions manifest dissimilar patterns, particularly in the near IR region. Comparison of reflectance of nevi with that of malignant melanomas results in a highly significant difference (P less than 10(-6)) between the two samples. Though interpretation of the spectra remains difficult as a result of the complexity of the optical processes of scattering and absorption, our results suggest that a detailed analysis of the reflectance spectrum may give clinically useful information, and could be utilized as an aid in clinical diagnosis of cutaneous pigmented lesions, especially where malignant melanoma is concerned. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Photochemistry and Photobiology
volume
53
issue
1
pages
77 - 84
publisher
American Society for Photobiology
external identifiers
  • pmid:2027910
  • scopus:0026053981
ISSN
0031-8655
DOI
10.1111/j.1751-1097.1991.tb08470.x
language
English
LU publication?
yes
id
2aa04260-86f9-4727-8388-04627cef7461 (old id 1105779)
date added to LUP
2008-08-04 11:28:20
date last changed
2017-01-01 04:40:10
@article{2aa04260-86f9-4727-8388-04627cef7461,
  abstract     = {Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of the different lesions manifest dissimilar patterns, particularly in the near IR region. Comparison of reflectance of nevi with that of malignant melanomas results in a highly significant difference (P less than 10(-6)) between the two samples. Though interpretation of the spectra remains difficult as a result of the complexity of the optical processes of scattering and absorption, our results suggest that a detailed analysis of the reflectance spectrum may give clinically useful information, and could be utilized as an aid in clinical diagnosis of cutaneous pigmented lesions, especially where malignant melanoma is concerned.},
  author       = {Marchesini, Renato and Brambilla, Marco and Clemente, Claudio and Maniezzo, Massimo and Sichirollo, Adele E and Testori, Alessandro and Venturoli, Daniele and Cascinelli, Natale},
  issn         = {0031-8655},
  language     = {eng},
  number       = {1},
  pages        = {77--84},
  publisher    = {American Society for Photobiology},
  series       = {Photochemistry and Photobiology},
  title        = {In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements},
  url          = {http://dx.doi.org/10.1111/j.1751-1097.1991.tb08470.x},
  volume       = {53},
  year         = {1991},
}