Advanced

Methanolstoffwechsel bei chronischem Alkoholismus

Soyka, M; Gilg, T; von Meyer, L and Ora, I (1991) In Wiener Klinische Wochenschrift 103(22). p.684-689
Abstract
Serum methanol concentrations (SMC) exceeding 10 mg/l are highly suggestive of long-term alcohol intoxication and can be considered as marker for chronic alcohol abuse. Endogenously formed or consumed methanol is almost exclusively metabolized by alcohol dehydrogenase. As long as blood alcohol concentrations exceed 0.2-0.5 g/l methanol cannot be metabolized and accumulates. In a prospective study on 78 patients admitted for alcohol detoxification, elevated SMC up to 78 mg/l were found, with a mean SMC of 29.4 mg/l. No correlation was demonstrated between SMC and severity of the alcohol withdrawal syndrome. Further clinical, forensic and biochemical aspects of methanol metabolism are discussed.
Please use this url to cite or link to this publication:
author
alternative title
Methanol metabolism in chronic alcoholism
publishing date
type
Contribution to journal
publication status
published
subject
in
Wiener Klinische Wochenschrift
volume
103
issue
22
pages
684 - 689
publisher
Springer
external identifiers
  • pmid:1776249
  • scopus:0026297001
ISSN
1613-7671
language
German
LU publication?
no
id
a8a1f4a2-794d-4f45-9a76-8f5427247020 (old id 1105926)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/1776249
date added to LUP
2013-10-17 16:01:20
date last changed
2017-01-01 05:00:45
@article{a8a1f4a2-794d-4f45-9a76-8f5427247020,
  abstract     = {Serum methanol concentrations (SMC) exceeding 10 mg/l are highly suggestive of long-term alcohol intoxication and can be considered as marker for chronic alcohol abuse. Endogenously formed or consumed methanol is almost exclusively metabolized by alcohol dehydrogenase. As long as blood alcohol concentrations exceed 0.2-0.5 g/l methanol cannot be metabolized and accumulates. In a prospective study on 78 patients admitted for alcohol detoxification, elevated SMC up to 78 mg/l were found, with a mean SMC of 29.4 mg/l. No correlation was demonstrated between SMC and severity of the alcohol withdrawal syndrome. Further clinical, forensic and biochemical aspects of methanol metabolism are discussed.},
  author       = {Soyka, M and Gilg, T and von Meyer, L and Ora, I},
  issn         = {1613-7671},
  language     = {ger},
  number       = {22},
  pages        = {684--689},
  publisher    = {Springer},
  series       = {Wiener Klinische Wochenschrift},
  title        = {Methanolstoffwechsel bei chronischem Alkoholismus},
  volume       = {103},
  year         = {1991},
}