Methanolstoffwechsel bei chronischem Alkoholismus
(1991) In Wiener Klinische Wochenschrift 103(22). p.684-689- Abstract
- Serum methanol concentrations (SMC) exceeding 10 mg/l are highly suggestive of long-term alcohol intoxication and can be considered as marker for chronic alcohol abuse. Endogenously formed or consumed methanol is almost exclusively metabolized by alcohol dehydrogenase. As long as blood alcohol concentrations exceed 0.2-0.5 g/l methanol cannot be metabolized and accumulates. In a prospective study on 78 patients admitted for alcohol detoxification, elevated SMC up to 78 mg/l were found, with a mean SMC of 29.4 mg/l. No correlation was demonstrated between SMC and severity of the alcohol withdrawal syndrome. Further clinical, forensic and biochemical aspects of methanol metabolism are discussed.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1105926
- author
- Soyka, M ; Gilg, T ; von Meyer, L and Ora, I
- alternative title
- Methanol metabolism in chronic alcoholism
- publishing date
- 1991
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Wiener Klinische Wochenschrift
- volume
- 103
- issue
- 22
- pages
- 684 - 689
- publisher
- Springer
- external identifiers
-
- pmid:1776249
- scopus:0026297001
- ISSN
- 1613-7671
- language
- German
- LU publication?
- no
- id
- a8a1f4a2-794d-4f45-9a76-8f5427247020 (old id 1105926)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/1776249
- date added to LUP
- 2016-04-01 12:17:23
- date last changed
- 2021-01-03 05:41:15
@article{a8a1f4a2-794d-4f45-9a76-8f5427247020, abstract = {{Serum methanol concentrations (SMC) exceeding 10 mg/l are highly suggestive of long-term alcohol intoxication and can be considered as marker for chronic alcohol abuse. Endogenously formed or consumed methanol is almost exclusively metabolized by alcohol dehydrogenase. As long as blood alcohol concentrations exceed 0.2-0.5 g/l methanol cannot be metabolized and accumulates. In a prospective study on 78 patients admitted for alcohol detoxification, elevated SMC up to 78 mg/l were found, with a mean SMC of 29.4 mg/l. No correlation was demonstrated between SMC and severity of the alcohol withdrawal syndrome. Further clinical, forensic and biochemical aspects of methanol metabolism are discussed.}}, author = {{Soyka, M and Gilg, T and von Meyer, L and Ora, I}}, issn = {{1613-7671}}, language = {{ger}}, number = {{22}}, pages = {{684--689}}, publisher = {{Springer}}, series = {{Wiener Klinische Wochenschrift}}, title = {{Methanolstoffwechsel bei chronischem Alkoholismus}}, url = {{http://www.ncbi.nlm.nih.gov/pubmed/1776249}}, volume = {{103}}, year = {{1991}}, }