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Passive smoking and childhood asthma. Urinary cotinine levels in children with asthma and in referents

Willers, Stefan LU ; Svenonius, E and Skarping, Gunnar LU (1991) In Allergy 46(5). p.330-334
Abstract
Passive exposure to tobacco smoke was assessed in children with asthma (age 3-15) and in referents. There was statistically significantly (P less than 0.0005) higher excretion of the nicotine metabolite, cotinine, in the urine of 49 children with asthma (geometric mean 10 ng/ml) compared with 77 referents (4.8 ng/ml). Maternal smoking was statistically significantly more prevalent among the asthmatics than among the referents (relative risk = RR = 2.6, 95% C1 = 1.2-5.3). In conclusion, the exposure to environmental tobacco smoke in asthmatic children was higher than among healthy children, indicating that passive smoking may be a predisposing and/or aggravating factor for childhood asthma.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cotinine, childhood asthma, involuntary, passive smoking, predisposing factor
in
Allergy
volume
46
issue
5
pages
330 - 334
publisher
Wiley-Blackwell
external identifiers
  • pmid:1928656
  • scopus:0025728042
ISSN
1398-9995
language
English
LU publication?
yes
id
6f8d15f5-3536-47fa-a1ff-1f296d093cbb (old id 1106045)
date added to LUP
2008-08-01 11:20:47
date last changed
2017-01-01 07:06:35
@article{6f8d15f5-3536-47fa-a1ff-1f296d093cbb,
  abstract     = {Passive exposure to tobacco smoke was assessed in children with asthma (age 3-15) and in referents. There was statistically significantly (P less than 0.0005) higher excretion of the nicotine metabolite, cotinine, in the urine of 49 children with asthma (geometric mean 10 ng/ml) compared with 77 referents (4.8 ng/ml). Maternal smoking was statistically significantly more prevalent among the asthmatics than among the referents (relative risk = RR = 2.6, 95% C1 = 1.2-5.3). In conclusion, the exposure to environmental tobacco smoke in asthmatic children was higher than among healthy children, indicating that passive smoking may be a predisposing and/or aggravating factor for childhood asthma.},
  author       = {Willers, Stefan and Svenonius, E and Skarping, Gunnar},
  issn         = {1398-9995},
  keyword      = {cotinine,childhood asthma,involuntary,passive smoking,predisposing factor},
  language     = {eng},
  number       = {5},
  pages        = {330--334},
  publisher    = {Wiley-Blackwell},
  series       = {Allergy},
  title        = {Passive smoking and childhood asthma. Urinary cotinine levels in children with asthma and in referents},
  volume       = {46},
  year         = {1991},
}