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In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions. II: Discriminant analysis between nevus and melanoma

Marchesini, R; Cascinelli, N; Brambilla, M; Clemente, C; Mascheroni, L; Pignoli, E; Testori, A and Venturoli, Daniele LU (1992) In Photochemistry and Photobiology 55(4). p.515-522
Abstract
Reflectance spectrophotometry from 420 to 780 nm on 31 primary melanoma and 31 benign nevi has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of melanoma and nevi manifest dissimilar patterns. From these spectra four variables, whose physical and/or physiological meanings remain to be investigated, have been derived. All of them are significantly different when compared between melanoma and nevi. A discriminant function between the two groups of lesions has been determined by using a stepwise discriminant analysis, resulting in a test with a sensitivity of 90.3% and a specificity of 77.4%. This method of discrimination between melanoma and nevi seems to have... (More)
Reflectance spectrophotometry from 420 to 780 nm on 31 primary melanoma and 31 benign nevi has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of melanoma and nevi manifest dissimilar patterns. From these spectra four variables, whose physical and/or physiological meanings remain to be investigated, have been derived. All of them are significantly different when compared between melanoma and nevi. A discriminant function between the two groups of lesions has been determined by using a stepwise discriminant analysis, resulting in a test with a sensitivity of 90.3% and a specificity of 77.4%. This method of discrimination between melanoma and nevi seems to have a discriminating power almost equal to that of a clinical judgement from a specialized medical doctor, thus suggesting a new method for screening skin pigmented lesions. (Less)
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
in
Photochemistry and Photobiology
volume
55
issue
4
pages
515 - 522
publisher
American Society for Photobiology
external identifiers
  • pmid:1620728
  • scopus:0026842788
ISSN
0031-8655
DOI
10.1111/j.1751-1097.1992.tb04272.x
language
English
LU publication?
no
id
937ca93e-11e2-4d2d-88c3-774d780b7cba (old id 1106462)
date added to LUP
2008-08-08 13:20:19
date last changed
2017-07-30 03:52:08
@article{937ca93e-11e2-4d2d-88c3-774d780b7cba,
  abstract     = {Reflectance spectrophotometry from 420 to 780 nm on 31 primary melanoma and 31 benign nevi has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of melanoma and nevi manifest dissimilar patterns. From these spectra four variables, whose physical and/or physiological meanings remain to be investigated, have been derived. All of them are significantly different when compared between melanoma and nevi. A discriminant function between the two groups of lesions has been determined by using a stepwise discriminant analysis, resulting in a test with a sensitivity of 90.3% and a specificity of 77.4%. This method of discrimination between melanoma and nevi seems to have a discriminating power almost equal to that of a clinical judgement from a specialized medical doctor, thus suggesting a new method for screening skin pigmented lesions.},
  author       = {Marchesini, R and Cascinelli, N and Brambilla, M and Clemente, C and Mascheroni, L and Pignoli, E and Testori, A and Venturoli, Daniele},
  issn         = {0031-8655},
  language     = {eng},
  number       = {4},
  pages        = {515--522},
  publisher    = {American Society for Photobiology},
  series       = {Photochemistry and Photobiology},
  title        = {In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions. II: Discriminant analysis between nevus and melanoma},
  url          = {http://dx.doi.org/10.1111/j.1751-1097.1992.tb04272.x},
  volume       = {55},
  year         = {1992},
}