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Low molecular weight heparin for thromboprophylaxis and epidural/spinal anaesthesia--is there a risk?

Bergqvist, D; Lindblad, B and Mätzsch, Thomas LU (1992) In Acta Anaesthesiologica Scandinavica 36(7). p.605-609
Abstract
This article reviews the problem of bleeding in connection with epidural/spinal anaesthesia, with special emphasis on the use of low molecular weight heparins for thromboprophylaxis. There are methodological difficulties to studying the problem in a scientifically correct way because of the rarity of the complication. However, from the data in the literature there are no indications of an increased risk in using the combination of low molecular weight heparin in prophylactic doses and epidural/spinal anaesthesia. So far, there is only a single case report, of spinal haematoma, although low molecular weight heparins have been used in combination with epidural/spinal anaesthesia in at least 1,000,000 patients. In controlled studies, at least... (More)
This article reviews the problem of bleeding in connection with epidural/spinal anaesthesia, with special emphasis on the use of low molecular weight heparins for thromboprophylaxis. There are methodological difficulties to studying the problem in a scientifically correct way because of the rarity of the complication. However, from the data in the literature there are no indications of an increased risk in using the combination of low molecular weight heparin in prophylactic doses and epidural/spinal anaesthesia. So far, there is only a single case report, of spinal haematoma, although low molecular weight heparins have been used in combination with epidural/spinal anaesthesia in at least 1,000,000 patients. In controlled studies, at least 10,000 patients have been given the combination without complications. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Anaesthesiologica Scandinavica
volume
36
issue
7
pages
605 - 609
publisher
Wiley-Blackwell
external identifiers
  • pmid:1332355
  • scopus:0026730327
ISSN
0001-5172
language
English
LU publication?
yes
id
5a034c69-5b9d-42f1-ba9a-46de93a3bde5 (old id 1106558)
date added to LUP
2008-07-31 10:26:29
date last changed
2017-08-06 03:38:10
@article{5a034c69-5b9d-42f1-ba9a-46de93a3bde5,
  abstract     = {This article reviews the problem of bleeding in connection with epidural/spinal anaesthesia, with special emphasis on the use of low molecular weight heparins for thromboprophylaxis. There are methodological difficulties to studying the problem in a scientifically correct way because of the rarity of the complication. However, from the data in the literature there are no indications of an increased risk in using the combination of low molecular weight heparin in prophylactic doses and epidural/spinal anaesthesia. So far, there is only a single case report, of spinal haematoma, although low molecular weight heparins have been used in combination with epidural/spinal anaesthesia in at least 1,000,000 patients. In controlled studies, at least 10,000 patients have been given the combination without complications.},
  author       = {Bergqvist, D and Lindblad, B and Mätzsch, Thomas},
  issn         = {0001-5172},
  language     = {eng},
  number       = {7},
  pages        = {605--609},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Anaesthesiologica Scandinavica},
  title        = {Low molecular weight heparin for thromboprophylaxis and epidural/spinal anaesthesia--is there a risk?},
  volume       = {36},
  year         = {1992},
}