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Differences in fiber number and fiber type proportion within fascicles. A quantitative morphological study of whole vastus lateralis muscle from childhood to old age

Sjöstrom, Michael; Lexell, Jan LU and Downham, David Y (1992) In Anatomical Record 234(2). p.183-189
Abstract
Data are presented on the number of fibers and the proportion of different fiber types within fascicles of whole vastus lateralis muscles from 5 male children, 5 to 15 years of age, and compared with results from 25 male adults, middle aged and old individuals. The results verify a difference in the proportion of fibers with different properties within a fascicle. The proportion of type 2 (fast twitch) fibers on the border of fascicles is larger than the proportion internally: the children have (P less than 0.01) greater difference than the adults and the middle aged, whereas the old have (P less than 0.001) less difference than the other age groups. The mean number of fibers per fascicle increases (P less than 0.05) from childhood to... (More)
Data are presented on the number of fibers and the proportion of different fiber types within fascicles of whole vastus lateralis muscles from 5 male children, 5 to 15 years of age, and compared with results from 25 male adults, middle aged and old individuals. The results verify a difference in the proportion of fibers with different properties within a fascicle. The proportion of type 2 (fast twitch) fibers on the border of fascicles is larger than the proportion internally: the children have (P less than 0.01) greater difference than the adults and the middle aged, whereas the old have (P less than 0.001) less difference than the other age groups. The mean number of fibers per fascicle increases (P less than 0.05) from childhood to adult age, and thereafter reduces (P less than 0.01). The results imply that fascicles continuously rearrange during the normal growth and development and the normal aging process. It is argued that the causes of the difference in fiber type proportions within fascicles are local factors in the muscle, secondary to the overall age related functional demands put on the fiber population. (Less)
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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Aging, Histocytochemistry, Microtomy, Muscles, Physiological adaption
in
Anatomical Record
volume
234
issue
2
pages
183 - 189
publisher
John Wiley & Sons
external identifiers
  • pmid:1416105
  • scopus:0026760352
ISSN
1097-0185
DOI
10.1002/ar.1092340205
language
English
LU publication?
no
id
e479af10-d7ef-4109-a7aa-8383d134e810 (old id 1106707)
date added to LUP
2008-08-12 09:02:08
date last changed
2017-06-04 03:39:07
@article{e479af10-d7ef-4109-a7aa-8383d134e810,
  abstract     = {Data are presented on the number of fibers and the proportion of different fiber types within fascicles of whole vastus lateralis muscles from 5 male children, 5 to 15 years of age, and compared with results from 25 male adults, middle aged and old individuals. The results verify a difference in the proportion of fibers with different properties within a fascicle. The proportion of type 2 (fast twitch) fibers on the border of fascicles is larger than the proportion internally: the children have (P less than 0.01) greater difference than the adults and the middle aged, whereas the old have (P less than 0.001) less difference than the other age groups. The mean number of fibers per fascicle increases (P less than 0.05) from childhood to adult age, and thereafter reduces (P less than 0.01). The results imply that fascicles continuously rearrange during the normal growth and development and the normal aging process. It is argued that the causes of the difference in fiber type proportions within fascicles are local factors in the muscle, secondary to the overall age related functional demands put on the fiber population.},
  author       = {Sjöstrom, Michael and Lexell, Jan and Downham, David Y},
  issn         = {1097-0185},
  keyword      = {Aging,Histocytochemistry,Microtomy,Muscles,Physiological adaption},
  language     = {eng},
  number       = {2},
  pages        = {183--189},
  publisher    = {John Wiley & Sons},
  series       = {Anatomical Record},
  title        = {Differences in fiber number and fiber type proportion within fascicles. A quantitative morphological study of whole vastus lateralis muscle from childhood to old age},
  url          = {http://dx.doi.org/10.1002/ar.1092340205},
  volume       = {234},
  year         = {1992},
}