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Diameter and compliance in the male human abdominal aorta: influence of age and aortic aneurysm

Länne, T; Sonesson, Björn LU ; Bergqvist, D; Bengtsson, H and Gustafsson, D (1992) In European Journal of Vascular Surgery 6(2). p.178-184
Abstract
In this study changes in the diameter and compliance of the distal abdominal aorta (76 healthy Caucasian males, 5-71 years old) were determined non-invasively and related to age by means of an ultrasound phase-locked echo-tracking system. The diameter of the aorta increased not only in the period between 5 and 25 years of age, but also by about 30% between the ages of 25 and 71. The pressure diameter curves at 25, 51 and 70 years were non-linear with flattening between 90 and 110 mmHg, and the slope of the curves declined with age. Thus, the pressure strain elastic modulus (Ep) and stiffness (beta) increased (i.e. compliance decreased) in an exponential manner according to age. A group of 37 males with aneurysmal widening of the distal... (More)
In this study changes in the diameter and compliance of the distal abdominal aorta (76 healthy Caucasian males, 5-71 years old) were determined non-invasively and related to age by means of an ultrasound phase-locked echo-tracking system. The diameter of the aorta increased not only in the period between 5 and 25 years of age, but also by about 30% between the ages of 25 and 71. The pressure diameter curves at 25, 51 and 70 years were non-linear with flattening between 90 and 110 mmHg, and the slope of the curves declined with age. Thus, the pressure strain elastic modulus (Ep) and stiffness (beta) increased (i.e. compliance decreased) in an exponential manner according to age. A group of 37 males with aneurysmal widening of the distal abdominal aorta had a significant increase in Ep when compared to an age-matched control group. Furthermore, the ranges for both Ep and beta were much larger in the aneurysm group than in the control group, indicating diversity in the pathogenesis of the disease. The non-invasive ultrasonic method of phase-locked echo-tracking is an appropriate method for studying compliance in major arteries under a variety of pathophysiological conditions. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Vascular Surgery
volume
6
issue
2
pages
178 - 184
publisher
Elsevier
external identifiers
  • pmid:1572458
  • scopus:0026566154
ISSN
0950-821X
language
English
LU publication?
yes
id
e073fdfe-a3d6-4d24-ab21-6420f631862c (old id 1106792)
date added to LUP
2008-08-04 09:40:53
date last changed
2017-11-12 03:54:56
@article{e073fdfe-a3d6-4d24-ab21-6420f631862c,
  abstract     = {In this study changes in the diameter and compliance of the distal abdominal aorta (76 healthy Caucasian males, 5-71 years old) were determined non-invasively and related to age by means of an ultrasound phase-locked echo-tracking system. The diameter of the aorta increased not only in the period between 5 and 25 years of age, but also by about 30% between the ages of 25 and 71. The pressure diameter curves at 25, 51 and 70 years were non-linear with flattening between 90 and 110 mmHg, and the slope of the curves declined with age. Thus, the pressure strain elastic modulus (Ep) and stiffness (beta) increased (i.e. compliance decreased) in an exponential manner according to age. A group of 37 males with aneurysmal widening of the distal abdominal aorta had a significant increase in Ep when compared to an age-matched control group. Furthermore, the ranges for both Ep and beta were much larger in the aneurysm group than in the control group, indicating diversity in the pathogenesis of the disease. The non-invasive ultrasonic method of phase-locked echo-tracking is an appropriate method for studying compliance in major arteries under a variety of pathophysiological conditions.},
  author       = {Länne, T and Sonesson, Björn and Bergqvist, D and Bengtsson, H and Gustafsson, D},
  issn         = {0950-821X},
  language     = {eng},
  number       = {2},
  pages        = {178--184},
  publisher    = {Elsevier},
  series       = {European Journal of Vascular Surgery},
  title        = {Diameter and compliance in the male human abdominal aorta: influence of age and aortic aneurysm},
  volume       = {6},
  year         = {1992},
}