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Exposure to environmental tobacco smoke in the household and urinary cotinine excretion, heavy metals retention, and lung function

Willers, Stefan LU ; Attewell, R; Bensryd, Inger LU ; Schutz, A; Skarping, Gunnar LU and Vahter, M (1992) In Archives of Environmental Health 47(5). p.357-563
Abstract
The relationship between urinary levels of cotinine (U-cotinine) and arsenic (U-As), blood levels of cadmium (B-Cd), blood levels of lead (B-Pb), lung function, and questionnaire data on smoking habits were studied in 107 parents and their 46 children (7-10 y of age). There was a statistically significant relationship between the reported amount of tobacco smoked and U-cotinine levels. Nonsmokers who were married to persons who smoked had three times higher U-cotinine levels than nonsmokers whose spouses did not smoke. There was a significant association between the number of parents who smoked in the family and the U-cotinine levels of children. If only one parent smoked, maternal smoking was of greater importance than paternal smoking.... (More)
The relationship between urinary levels of cotinine (U-cotinine) and arsenic (U-As), blood levels of cadmium (B-Cd), blood levels of lead (B-Pb), lung function, and questionnaire data on smoking habits were studied in 107 parents and their 46 children (7-10 y of age). There was a statistically significant relationship between the reported amount of tobacco smoked and U-cotinine levels. Nonsmokers who were married to persons who smoked had three times higher U-cotinine levels than nonsmokers whose spouses did not smoke. There was a significant association between the number of parents who smoked in the family and the U-cotinine levels of children. If only one parent smoked, maternal smoking was of greater importance than paternal smoking. There was also an association between U-cotinine and B-Cd. A study of lung function in the children revealed that vital capacity and functional residual capacity (corrected for sex, age, and height) increased as the number of parents who smoked increased. Therefore, the present study showed that (1) U-cotinine was a useful index of active smoking and environmental tobacco smoke exposure in adults and children, (2) U-cotinine was associated with the blood concentration of cadmium, and (3) environmental tobacco smoke exposure was associated with changes in lung function of children. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Archives of Environmental Health
volume
47
issue
5
pages
357 - 563
publisher
Heldref Publications
external identifiers
  • pmid:1444598
  • scopus:0026460060
ISSN
0003-9896
language
English
LU publication?
yes
id
12ee5987-18ad-4c4e-a97f-8fcf793cdf9d (old id 1106807)
date added to LUP
2008-08-12 09:45:17
date last changed
2017-07-30 04:32:31
@article{12ee5987-18ad-4c4e-a97f-8fcf793cdf9d,
  abstract     = {The relationship between urinary levels of cotinine (U-cotinine) and arsenic (U-As), blood levels of cadmium (B-Cd), blood levels of lead (B-Pb), lung function, and questionnaire data on smoking habits were studied in 107 parents and their 46 children (7-10 y of age). There was a statistically significant relationship between the reported amount of tobacco smoked and U-cotinine levels. Nonsmokers who were married to persons who smoked had three times higher U-cotinine levels than nonsmokers whose spouses did not smoke. There was a significant association between the number of parents who smoked in the family and the U-cotinine levels of children. If only one parent smoked, maternal smoking was of greater importance than paternal smoking. There was also an association between U-cotinine and B-Cd. A study of lung function in the children revealed that vital capacity and functional residual capacity (corrected for sex, age, and height) increased as the number of parents who smoked increased. Therefore, the present study showed that (1) U-cotinine was a useful index of active smoking and environmental tobacco smoke exposure in adults and children, (2) U-cotinine was associated with the blood concentration of cadmium, and (3) environmental tobacco smoke exposure was associated with changes in lung function of children.},
  author       = {Willers, Stefan and Attewell, R and Bensryd, Inger and Schutz, A and Skarping, Gunnar and Vahter, M},
  issn         = {0003-9896},
  language     = {eng},
  number       = {5},
  pages        = {357--563},
  publisher    = {Heldref Publications},
  series       = {Archives of Environmental Health},
  title        = {Exposure to environmental tobacco smoke in the household and urinary cotinine excretion, heavy metals retention, and lung function},
  volume       = {47},
  year         = {1992},
}