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Inhaled methacholine does not influence the cellular composition of bronchoalveolar lavage fluid

Söderberg, M; Lundgren, R; Bjermer, Leif LU and Angstrom, T (1993) In Allergy 48(3). p.173-176
Abstract
A methacholine or a histamine test is often used to quantitate bronchial responsiveness, in studies investigating the influence of various inhaled stimuli on the responsiveness and composition of bronchoalveolar lavage (BAL) fluid. Histamine has been shown to evoke an inflammatory cell response in BAL fluid. In order to test the influence of the methacholine test on the cellular composition of BAL fluid, we investigated 14 healthy, nonsmoking volunteers with a methacholine test 24 h before performing a BAL. The results showed no significant changes in the cellular composition of BAL fluid, as compared with control BAL in the same persons.
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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
bronchoalveolar lavage, histamine test, methacholine test, lymphocytes, mast cells
in
Allergy
volume
48
issue
3
pages
173 - 176
publisher
Wiley-Blackwell
external identifiers
  • pmid:8506984
  • scopus:0027175105
ISSN
1398-9995
DOI
10.1111/j.1398-9995.1993.tb00709.x
language
English
LU publication?
no
id
90b99cd0-a809-49fd-8795-25aa2497be3d (old id 1107074)
date added to LUP
2008-07-30 10:26:44
date last changed
2017-01-01 07:22:02
@article{90b99cd0-a809-49fd-8795-25aa2497be3d,
  abstract     = {A methacholine or a histamine test is often used to quantitate bronchial responsiveness, in studies investigating the influence of various inhaled stimuli on the responsiveness and composition of bronchoalveolar lavage (BAL) fluid. Histamine has been shown to evoke an inflammatory cell response in BAL fluid. In order to test the influence of the methacholine test on the cellular composition of BAL fluid, we investigated 14 healthy, nonsmoking volunteers with a methacholine test 24 h before performing a BAL. The results showed no significant changes in the cellular composition of BAL fluid, as compared with control BAL in the same persons.},
  author       = {Söderberg, M and Lundgren, R and Bjermer, Leif and Angstrom, T},
  issn         = {1398-9995},
  keyword      = {bronchoalveolar lavage,histamine test,methacholine test,lymphocytes,mast cells},
  language     = {eng},
  number       = {3},
  pages        = {173--176},
  publisher    = {Wiley-Blackwell},
  series       = {Allergy},
  title        = {Inhaled methacholine does not influence the cellular composition of bronchoalveolar lavage fluid},
  url          = {http://dx.doi.org/10.1111/j.1398-9995.1993.tb00709.x},
  volume       = {48},
  year         = {1993},
}