Advanced

Bronchoscopic diagnosis of pulmonary infections in a heterogeneous, nonselected group of patients

Ekdahl, Karl; Eriksson, Leif LU ; Rollof, Jan LU ; Miörner, Håkan LU ; Griph, Håkan and Löfgren, Bengt LU (1993) In Chest 103(6). p.1743-1748
Abstract
Fiberoptic bronchoscopy with bronchoalveolar lavage and protected specimen brush technique has become an established method for etiologic diagnosis in severe forms of pulmonary infections during recent years. In this study, including 62 bronchoscopies in 53 patients, a standardized program, covering all important pulmonary pathogens, has been evaluated in a heterogeneous group of patients. Results providing therapeutic guidelines were obtained in 53 percent (16/30) of the immunocompromised patients (including 5 bronchoscopies on HIV-positive patients), but only 19 percent (6/32) of the immunocompetent patients (p < 0.001). We conclude that bronchoscopy is of great value for diagnosing pulmonary infections in immunocompromised patients.... (More)
Fiberoptic bronchoscopy with bronchoalveolar lavage and protected specimen brush technique has become an established method for etiologic diagnosis in severe forms of pulmonary infections during recent years. In this study, including 62 bronchoscopies in 53 patients, a standardized program, covering all important pulmonary pathogens, has been evaluated in a heterogeneous group of patients. Results providing therapeutic guidelines were obtained in 53 percent (16/30) of the immunocompromised patients (including 5 bronchoscopies on HIV-positive patients), but only 19 percent (6/32) of the immunocompetent patients (p < 0.001). We conclude that bronchoscopy is of great value for diagnosing pulmonary infections in immunocompromised patients. In immunocompetent patients, the diagnostic yield is lower and the indication for bronchoscopy must be established for each individual patient based on clinical importance, resources, and risk. When bronchoscopy is performed, we believe that a standardized program like ours reduces the risk of missing important pathogens. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Chest
volume
103
issue
6
pages
1743 - 1748
publisher
American College of Chest Physicians
external identifiers
  • pmid:8404094
  • scopus:0027238257
ISSN
1931-3543
language
English
LU publication?
yes
id
d6f37e4f-8fcf-406a-b3d3-20911ab0ee51 (old id 1107273)
alternative location
http://www.chestjournal.org/cgi/reprint/103/6/1743
date added to LUP
2008-07-30 14:45:43
date last changed
2017-07-09 04:23:34
@article{d6f37e4f-8fcf-406a-b3d3-20911ab0ee51,
  abstract     = {Fiberoptic bronchoscopy with bronchoalveolar lavage and protected specimen brush technique has become an established method for etiologic diagnosis in severe forms of pulmonary infections during recent years. In this study, including 62 bronchoscopies in 53 patients, a standardized program, covering all important pulmonary pathogens, has been evaluated in a heterogeneous group of patients. Results providing therapeutic guidelines were obtained in 53 percent (16/30) of the immunocompromised patients (including 5 bronchoscopies on HIV-positive patients), but only 19 percent (6/32) of the immunocompetent patients (p &lt; 0.001). We conclude that bronchoscopy is of great value for diagnosing pulmonary infections in immunocompromised patients. In immunocompetent patients, the diagnostic yield is lower and the indication for bronchoscopy must be established for each individual patient based on clinical importance, resources, and risk. When bronchoscopy is performed, we believe that a standardized program like ours reduces the risk of missing important pathogens.},
  author       = {Ekdahl, Karl and Eriksson, Leif and Rollof, Jan and Miörner, Håkan and Griph, Håkan and Löfgren, Bengt},
  issn         = {1931-3543},
  language     = {eng},
  number       = {6},
  pages        = {1743--1748},
  publisher    = {American College of Chest Physicians},
  series       = {Chest},
  title        = {Bronchoscopic diagnosis of pulmonary infections in a heterogeneous, nonselected group of patients},
  volume       = {103},
  year         = {1993},
}