Advanced

A four-year follow-up study on the incidence of diabetic retinopathy in older onset diabetes mellitus

Agardh, Elisabet LU ; Agardh, Carl-David LU ; Koul, S and Torffvit, Ole LU (1994) In Diabetic Medicine 11(3). p.273-278
Abstract
Out of 369 diabetic patients with an age at onset of diabetes > or = 30 years previously studied, 325 (88%) were included in an ophthalmological follow-up examination 4 years later. In patients treated with oral drugs at baseline, the incidence of any type of retinopathy was 30.8% and of severe retinopathy 5.7%. All patients who developed severe retinopathy received insulin during the follow-up period. At baseline, duration of diabetes, diastolic blood pressure, and signs of nephropathy (p < 0.05 in all cases) as well as degree of metabolic control (p < 0.01) differed between patients who developed retinopathy and those who did not. At follow-up, there were no longer any differences regarding degree of metabolic control and... (More)
Out of 369 diabetic patients with an age at onset of diabetes > or = 30 years previously studied, 325 (88%) were included in an ophthalmological follow-up examination 4 years later. In patients treated with oral drugs at baseline, the incidence of any type of retinopathy was 30.8% and of severe retinopathy 5.7%. All patients who developed severe retinopathy received insulin during the follow-up period. At baseline, duration of diabetes, diastolic blood pressure, and signs of nephropathy (p < 0.05 in all cases) as well as degree of metabolic control (p < 0.01) differed between patients who developed retinopathy and those who did not. At follow-up, there were no longer any differences regarding degree of metabolic control and diastolic blood pressure. In patients treated with insulin at baseline, the incidence of any type of retinopathy was 41.0% and of severe retinopathy 16.1%. At baseline, duration of diabetes (p < 0.01), degree of metabolic control, and insulin dosage (p < 0.05 in both cases) differed between patients who developed retinopathy and those who did not. At follow-up, there was no longer any difference in insulin dosage. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diabetic Medicine
volume
11
issue
3
pages
273 - 278
publisher
Wiley-Blackwell
external identifiers
  • pmid:8033526
  • scopus:0028205546
ISSN
1464-5491
language
English
LU publication?
yes
id
836c4ced-6fae-47bf-88a8-7c088d4c0928 (old id 1108040)
date added to LUP
2008-07-23 11:43:18
date last changed
2017-01-01 06:53:42
@article{836c4ced-6fae-47bf-88a8-7c088d4c0928,
  abstract     = {Out of 369 diabetic patients with an age at onset of diabetes &gt; or = 30 years previously studied, 325 (88%) were included in an ophthalmological follow-up examination 4 years later. In patients treated with oral drugs at baseline, the incidence of any type of retinopathy was 30.8% and of severe retinopathy 5.7%. All patients who developed severe retinopathy received insulin during the follow-up period. At baseline, duration of diabetes, diastolic blood pressure, and signs of nephropathy (p &lt; 0.05 in all cases) as well as degree of metabolic control (p &lt; 0.01) differed between patients who developed retinopathy and those who did not. At follow-up, there were no longer any differences regarding degree of metabolic control and diastolic blood pressure. In patients treated with insulin at baseline, the incidence of any type of retinopathy was 41.0% and of severe retinopathy 16.1%. At baseline, duration of diabetes (p &lt; 0.01), degree of metabolic control, and insulin dosage (p &lt; 0.05 in both cases) differed between patients who developed retinopathy and those who did not. At follow-up, there was no longer any difference in insulin dosage.},
  author       = {Agardh, Elisabet and Agardh, Carl-David and Koul, S and Torffvit, Ole},
  issn         = {1464-5491},
  language     = {eng},
  number       = {3},
  pages        = {273--278},
  publisher    = {Wiley-Blackwell},
  series       = {Diabetic Medicine},
  title        = {A four-year follow-up study on the incidence of diabetic retinopathy in older onset diabetes mellitus},
  volume       = {11},
  year         = {1994},
}