Advanced

Radiological investigation of neurofibromatosis type 2

Åkeson, Per LU and Holtås, Stig LU (1994) In Neuroradiology 36(2). p.107-110
Abstract
The radiological findings in six patients fulfilling the criteria of neurofibromatosis type 2 (NF2) were reviewed. Subtle cutaneous lesions were found in three. All patients had bilateral acoustic schwannomas; two had small acoustic tumours and normal hearing. In these patients the presenting symptoms were caused by multiple intracranial meningiomas and spinal neurofibromas, respectively, whereas the remaining four patients presented with hearing loss. Two patients had other cranial nerve tumours. Three patients had rapidly growing multiple intracranial meningiomas; two had multiple spinal neurofibromas and one a spinal meningioma. NF2 is a rare disease with few cutaneous but frequent, typical radiological findings in the central nervous... (More)
The radiological findings in six patients fulfilling the criteria of neurofibromatosis type 2 (NF2) were reviewed. Subtle cutaneous lesions were found in three. All patients had bilateral acoustic schwannomas; two had small acoustic tumours and normal hearing. In these patients the presenting symptoms were caused by multiple intracranial meningiomas and spinal neurofibromas, respectively, whereas the remaining four patients presented with hearing loss. Two patients had other cranial nerve tumours. Three patients had rapidly growing multiple intracranial meningiomas; two had multiple spinal neurofibromas and one a spinal meningioma. NF2 is a rare disease with few cutaneous but frequent, typical radiological findings in the central nervous system. The presenting symptom is most commonly hearing loss due to acoustic schwannomas, although symptoms emanating from other intracranial or tumours are not uncommon. The discovery of multiple meningiomas or multiple spinal neurofibromas without cutaneous lesions should initiate a search for acoustic schwannomas even when the patient has normal hearing. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Neurofibromatosis, NF2, Multiple Meningioma, MRI
in
Neuroradiology
volume
36
issue
2
pages
107 - 110
publisher
Springer Verlag
external identifiers
  • pmid:8183445
  • scopus:0028079549
ISSN
1432-1920
DOI
10.1007/BF00588071
language
English
LU publication?
yes
id
fa1c27a0-ad0e-45e1-8d45-0a12c8cc0529 (old id 1108163)
date added to LUP
2008-07-23 14:54:45
date last changed
2017-01-01 05:15:02
@article{fa1c27a0-ad0e-45e1-8d45-0a12c8cc0529,
  abstract     = {The radiological findings in six patients fulfilling the criteria of neurofibromatosis type 2 (NF2) were reviewed. Subtle cutaneous lesions were found in three. All patients had bilateral acoustic schwannomas; two had small acoustic tumours and normal hearing. In these patients the presenting symptoms were caused by multiple intracranial meningiomas and spinal neurofibromas, respectively, whereas the remaining four patients presented with hearing loss. Two patients had other cranial nerve tumours. Three patients had rapidly growing multiple intracranial meningiomas; two had multiple spinal neurofibromas and one a spinal meningioma. NF2 is a rare disease with few cutaneous but frequent, typical radiological findings in the central nervous system. The presenting symptom is most commonly hearing loss due to acoustic schwannomas, although symptoms emanating from other intracranial or tumours are not uncommon. The discovery of multiple meningiomas or multiple spinal neurofibromas without cutaneous lesions should initiate a search for acoustic schwannomas even when the patient has normal hearing.},
  author       = {Åkeson, Per and Holtås, Stig},
  issn         = {1432-1920},
  keyword      = {Neurofibromatosis,NF2,Multiple Meningioma,MRI},
  language     = {eng},
  number       = {2},
  pages        = {107--110},
  publisher    = {Springer Verlag},
  series       = {Neuroradiology},
  title        = {Radiological investigation of neurofibromatosis type 2},
  url          = {http://dx.doi.org/10.1007/BF00588071},
  volume       = {36},
  year         = {1994},
}