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Hepatitis E virus infections in patients with acute hepatitis non-A-D in Sweden

Johansson, Hugo LU ; Mushahwar, Isa K; Norkrans, Gunnar; Weiland, Ola and Nordenfelt, Erik (1995) In Scandinavian Journal of Infectious Diseases 27(6). p.543-546
Abstract
A total of 12 patients previously treated for acute hepatitis of unknown aetiology were retrospectively found to be anti-hepatitis E virus (HEV) IgG-positive. Four patients were anti-HEV IgM- and IgG-positive consistent with an acute HEV infection. All 4 had travelled to or were immigrants from HEV-endemic countries. One anti-HEV IgM-negative patient seroconverted from anti-HEV IgG-negative to positive and 3 from anti-HEV IgG-positive to negative in 2 consecutive serum samples. Of the remaining 4 patients without anti-HEV IgM, 3 had a history of recent travel to an HEV-endemic country. Most patients were young adults and all but 1 recovered from the hepatitis. One patient with a fulminant hepatitis was anti-HEV IgG-positive when tested 4... (More)
A total of 12 patients previously treated for acute hepatitis of unknown aetiology were retrospectively found to be anti-hepatitis E virus (HEV) IgG-positive. Four patients were anti-HEV IgM- and IgG-positive consistent with an acute HEV infection. All 4 had travelled to or were immigrants from HEV-endemic countries. One anti-HEV IgM-negative patient seroconverted from anti-HEV IgG-negative to positive and 3 from anti-HEV IgG-positive to negative in 2 consecutive serum samples. Of the remaining 4 patients without anti-HEV IgM, 3 had a history of recent travel to an HEV-endemic country. Most patients were young adults and all but 1 recovered from the hepatitis. One patient with a fulminant hepatitis was anti-HEV IgG-positive when tested 4 months after a journey to Turkey. She died from her fulminant hepatitis shortly after admission. All the other patients but 1 normalized their serum liver enzymes within 1-2 months after the onset of disease. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Scandinavian Journal of Infectious Diseases
volume
27
issue
6
pages
543 - 546
publisher
Informa Healthcare
external identifiers
  • pmid:8685630
  • scopus:0029552950
ISSN
1651-1980
DOI
10.3109/00365549509047064
language
English
LU publication?
yes
id
f0e581b9-18cf-41d4-982e-349c6f4ed02f (old id 1109031)
date added to LUP
2008-07-25 12:36:14
date last changed
2017-08-06 04:29:49
@article{f0e581b9-18cf-41d4-982e-349c6f4ed02f,
  abstract     = {A total of 12 patients previously treated for acute hepatitis of unknown aetiology were retrospectively found to be anti-hepatitis E virus (HEV) IgG-positive. Four patients were anti-HEV IgM- and IgG-positive consistent with an acute HEV infection. All 4 had travelled to or were immigrants from HEV-endemic countries. One anti-HEV IgM-negative patient seroconverted from anti-HEV IgG-negative to positive and 3 from anti-HEV IgG-positive to negative in 2 consecutive serum samples. Of the remaining 4 patients without anti-HEV IgM, 3 had a history of recent travel to an HEV-endemic country. Most patients were young adults and all but 1 recovered from the hepatitis. One patient with a fulminant hepatitis was anti-HEV IgG-positive when tested 4 months after a journey to Turkey. She died from her fulminant hepatitis shortly after admission. All the other patients but 1 normalized their serum liver enzymes within 1-2 months after the onset of disease.},
  author       = {Johansson, Hugo and Mushahwar, Isa K and Norkrans, Gunnar and Weiland, Ola and Nordenfelt, Erik},
  issn         = {1651-1980},
  language     = {eng},
  number       = {6},
  pages        = {543--546},
  publisher    = {Informa Healthcare},
  series       = {Scandinavian Journal of Infectious Diseases},
  title        = {Hepatitis E virus infections in patients with acute hepatitis non-A-D in Sweden},
  url          = {http://dx.doi.org/10.3109/00365549509047064},
  volume       = {27},
  year         = {1995},
}