Contact allergy to the active ingredients of Bioban P 1487
(1996) In Contact Dermatitis 35(3). p.141-145- Abstract
- Bioban P 1487, consisting of the 2 active ingredients 4-(2-nitrobutyl)-morpholine (M) and 4,4'-(2-ethyl-2-nitro-1,3-propanediyl)-bis morpholine (DM), is a preservative recommended for mental working fluids. The aims of this study were to assess the frequency of contact allergy to Bioban P 1487, when added to a standard patch test series, as well as to test the individual active ingredients in patients sensitized to Bioban P 1487. Of the patients consecutively tested, 1.5% reacted positively to Bioban P 1487. Positive test reactions were noted in only 4 of 12 Bioban P 1487-sensitized patients tested with the individual active ingredients. Both active ingredients are contact sensitizers, but in most patients with this contact allergy it... (More)
- Bioban P 1487, consisting of the 2 active ingredients 4-(2-nitrobutyl)-morpholine (M) and 4,4'-(2-ethyl-2-nitro-1,3-propanediyl)-bis morpholine (DM), is a preservative recommended for mental working fluids. The aims of this study were to assess the frequency of contact allergy to Bioban P 1487, when added to a standard patch test series, as well as to test the individual active ingredients in patients sensitized to Bioban P 1487. Of the patients consecutively tested, 1.5% reacted positively to Bioban P 1487. Positive test reactions were noted in only 4 of 12 Bioban P 1487-sensitized patients tested with the individual active ingredients. Both active ingredients are contact sensitizers, but in most patients with this contact allergy it remains difficult to identify the sensitizing hapten. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1110433
- author
- Gruvberger, Birgitta LU ; Bruze, Magnus LU and Zimerson, Erik LU
- organization
- publishing date
- 1996
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Bioban P 1487, CAS 2224-44-4, CAS 1854-23-5, allergic contact dermatitis, delayed hypersensitivity, 4, 4'-(2-ethyl-2-nitro-1, 3-propanediyl)-bis morpholine, high-performance liquid chromatography, metal working fluids, 4-(2-nitrobutyl)-morpholine, preservatives, occupational, engineering industry
- in
- Contact Dermatitis
- volume
- 35
- issue
- 3
- pages
- 141 - 145
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:8930473
- scopus:0029805649
- ISSN
- 0105-1873
- DOI
- 10.1111/j.1600-0536.1996.tb02331.x
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Occupational and Environmental Dermatology Unit (013241310), Pediatrics/Urology/Gynecology/Endocrinology (013240400)
- id
- 4305336b-635e-4032-ab4f-b24f4ed6bfdb (old id 1110433)
- date added to LUP
- 2016-04-01 11:40:14
- date last changed
- 2022-01-26 08:28:08
@article{4305336b-635e-4032-ab4f-b24f4ed6bfdb, abstract = {{Bioban P 1487, consisting of the 2 active ingredients 4-(2-nitrobutyl)-morpholine (M) and 4,4'-(2-ethyl-2-nitro-1,3-propanediyl)-bis morpholine (DM), is a preservative recommended for mental working fluids. The aims of this study were to assess the frequency of contact allergy to Bioban P 1487, when added to a standard patch test series, as well as to test the individual active ingredients in patients sensitized to Bioban P 1487. Of the patients consecutively tested, 1.5% reacted positively to Bioban P 1487. Positive test reactions were noted in only 4 of 12 Bioban P 1487-sensitized patients tested with the individual active ingredients. Both active ingredients are contact sensitizers, but in most patients with this contact allergy it remains difficult to identify the sensitizing hapten.}}, author = {{Gruvberger, Birgitta and Bruze, Magnus and Zimerson, Erik}}, issn = {{0105-1873}}, keywords = {{Bioban P 1487; CAS 2224-44-4; CAS 1854-23-5; allergic contact dermatitis; delayed hypersensitivity; 4; 4'-(2-ethyl-2-nitro-1; 3-propanediyl)-bis morpholine; high-performance liquid chromatography; metal working fluids; 4-(2-nitrobutyl)-morpholine; preservatives; occupational; engineering industry}}, language = {{eng}}, number = {{3}}, pages = {{141--145}}, publisher = {{Wiley-Blackwell}}, series = {{Contact Dermatitis}}, title = {{Contact allergy to the active ingredients of Bioban P 1487}}, url = {{http://dx.doi.org/10.1111/j.1600-0536.1996.tb02331.x}}, doi = {{10.1111/j.1600-0536.1996.tb02331.x}}, volume = {{35}}, year = {{1996}}, }