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Preoperative staging of rectal carcinoma using double-contrast MR imaging. Technical aspects and early clinical experiences

Wallengren, Nils-Olof LU ; Holtås, Stig LU and Andren-Sandberg, A (1996) In Acta Radiologica 37(5). p.791-798
Abstract
PURPOSE: To improve preoperative staging of rectal carcinoma with MR imaging, using a double-contrast technique. MATERIAL AND METHODS: Imaging was performed in 12 patients before and after i.v. injection of Gd-DTPA and rectal administration of a superparamagnetic contrast medium, mainly containing magnetite. The diagnostic information was evaluated and compared with findings at surgery and histopathological analysis. RESULTS: The superparamagnetic contrast medium enema caused a distension of the rectum and intraluminal signal void, whereas Gd-DTPA enhanced the mucosa in T1-weighted images. This allowed an evaluation of the normal rectal wall and separation of the mucosa, tunica muscularis and perirectal space in all cases, which was not... (More)
PURPOSE: To improve preoperative staging of rectal carcinoma with MR imaging, using a double-contrast technique. MATERIAL AND METHODS: Imaging was performed in 12 patients before and after i.v. injection of Gd-DTPA and rectal administration of a superparamagnetic contrast medium, mainly containing magnetite. The diagnostic information was evaluated and compared with findings at surgery and histopathological analysis. RESULTS: The superparamagnetic contrast medium enema caused a distension of the rectum and intraluminal signal void, whereas Gd-DTPA enhanced the mucosa in T1-weighted images. This allowed an evaluation of the normal rectal wall and separation of the mucosa, tunica muscularis and perirectal space in all cases, which was not possible in T1- or T2-weighted precontrast images. The rectal carcinoma could be delineated and tumor invasion to the rectal wall determined in all cases. The findings in postcontrast MR corresponded with the findings at histopathological examination in 11 of 12 patients. The histopathological examination in one patient revealed metastases (< 1 cm) in regional lymph nodes, too small to be identified in pre- or postcontrast MR images. CONCLUSION: Double-contrast-enhanced MR imaging allows evaluation of the normal rectal wall and preoperative staging of rectal carcinoma. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Radiologica
volume
37
issue
5
pages
791 - 798
publisher
John Wiley & Sons
external identifiers
  • pmid:8915295
  • scopus:0030237283
ISSN
1600-0455
language
English
LU publication?
yes
id
9d8b1221-c4d7-4c71-946c-713e3bd18d42 (old id 1110441)
date added to LUP
2008-07-30 09:42:45
date last changed
2017-01-01 06:48:31
@article{9d8b1221-c4d7-4c71-946c-713e3bd18d42,
  abstract     = {PURPOSE: To improve preoperative staging of rectal carcinoma with MR imaging, using a double-contrast technique. MATERIAL AND METHODS: Imaging was performed in 12 patients before and after i.v. injection of Gd-DTPA and rectal administration of a superparamagnetic contrast medium, mainly containing magnetite. The diagnostic information was evaluated and compared with findings at surgery and histopathological analysis. RESULTS: The superparamagnetic contrast medium enema caused a distension of the rectum and intraluminal signal void, whereas Gd-DTPA enhanced the mucosa in T1-weighted images. This allowed an evaluation of the normal rectal wall and separation of the mucosa, tunica muscularis and perirectal space in all cases, which was not possible in T1- or T2-weighted precontrast images. The rectal carcinoma could be delineated and tumor invasion to the rectal wall determined in all cases. The findings in postcontrast MR corresponded with the findings at histopathological examination in 11 of 12 patients. The histopathological examination in one patient revealed metastases (&lt; 1 cm) in regional lymph nodes, too small to be identified in pre- or postcontrast MR images. CONCLUSION: Double-contrast-enhanced MR imaging allows evaluation of the normal rectal wall and preoperative staging of rectal carcinoma.},
  author       = {Wallengren, Nils-Olof and Holtås, Stig and Andren-Sandberg, A},
  issn         = {1600-0455},
  language     = {eng},
  number       = {5},
  pages        = {791--798},
  publisher    = {John Wiley & Sons},
  series       = {Acta Radiologica},
  title        = {Preoperative staging of rectal carcinoma using double-contrast MR imaging. Technical aspects and early clinical experiences},
  volume       = {37},
  year         = {1996},
}