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A new liposomal contrast medium for CT of the liver. An imaging study in a rabbit tumour model

Leander, Peter LU (1996) In Acta Radiologica 37(1). p.63-68
Abstract
A new type of liposomal liver-specific contrast medium was studied in an experimental tumour model. Rabbits were inoculated with VX2-carcinoma directly in the liver of laparotomy. CT studies were carried out 14 days after inoculation. The liver-specific contrast medium consisted of a suspension of liposomes in a 100 mg I/ml iodixanol solution, with equal amounts of encapsulated and nonencapsulated iodixanol. It was administered at a dose of 200 mg I/kg. The contrast of normal liver tissue to tumorous tissue was significantly increased by contrast medium administration, the increase being largest 10 min after injection.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Radiologica
volume
37
issue
1
pages
63 - 68
publisher
John Wiley & Sons
external identifiers
  • pmid:8611327
  • scopus:0029685559
ISSN
1600-0455
language
English
LU publication?
yes
id
264b8f0a-79cc-4d80-b832-9e8f47816530 (old id 1110569)
date added to LUP
2008-07-25 14:31:32
date last changed
2017-01-01 07:22:26
@article{264b8f0a-79cc-4d80-b832-9e8f47816530,
  abstract     = {A new type of liposomal liver-specific contrast medium was studied in an experimental tumour model. Rabbits were inoculated with VX2-carcinoma directly in the liver of laparotomy. CT studies were carried out 14 days after inoculation. The liver-specific contrast medium consisted of a suspension of liposomes in a 100 mg I/ml iodixanol solution, with equal amounts of encapsulated and nonencapsulated iodixanol. It was administered at a dose of 200 mg I/kg. The contrast of normal liver tissue to tumorous tissue was significantly increased by contrast medium administration, the increase being largest 10 min after injection.},
  author       = {Leander, Peter},
  issn         = {1600-0455},
  language     = {eng},
  number       = {1},
  pages        = {63--68},
  publisher    = {John Wiley & Sons},
  series       = {Acta Radiologica},
  title        = {A new liposomal contrast medium for CT of the liver. An imaging study in a rabbit tumour model},
  volume       = {37},
  year         = {1996},
}