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Transient hypertriglyceridemia of infancy

Nilsson, A; Ortqvist, E; Lagercrantz, H; Nilsson-Ehle, Peter LU and Henter, J I (1996) In Acta Pædiatrica 85(12). p.1508-1510
Abstract
A premature boy who had suffered from IRDS, bronchopulmonary dysplasia and retinopathy of prematurity developed massive hypertriglyceridemia (48.1 mmol/L) together with moderate hypercholesterolemia (12.6 mmol/L) at 5 months of age. Lipoprotein electrophoresis revealed a marked elevation of the level of the very low density lipoprotein fraction. There was a moderate decrease in the activity of a lipolytic enzyme, lipoprotein lipase (LPL). The child had neither liver or renal disorder nor any inflammatory disease. The hyperlipidemia disappeared spontaneously at the age of 3 years. The cause of the decreased LPL activity could not be established. A partial genetic deficiency in lipoprotein lipase appears the most likely explanation, since no... (More)
A premature boy who had suffered from IRDS, bronchopulmonary dysplasia and retinopathy of prematurity developed massive hypertriglyceridemia (48.1 mmol/L) together with moderate hypercholesterolemia (12.6 mmol/L) at 5 months of age. Lipoprotein electrophoresis revealed a marked elevation of the level of the very low density lipoprotein fraction. There was a moderate decrease in the activity of a lipolytic enzyme, lipoprotein lipase (LPL). The child had neither liver or renal disorder nor any inflammatory disease. The hyperlipidemia disappeared spontaneously at the age of 3 years. The cause of the decreased LPL activity could not be established. A partial genetic deficiency in lipoprotein lipase appears the most likely explanation, since no signs of secondary lowering of LPL activity could be found. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Hypertriglyceridemia, infancy, lipoprotein lipase
in
Acta Pædiatrica
volume
85
issue
12
pages
1508 - 1510
publisher
Taylor & Francis
external identifiers
  • pmid:9001670
  • scopus:0029828644
ISSN
1651-2227
DOI
10.1111/j.1651-2227.1996.tb13964.x
language
English
LU publication?
yes
id
e194c581-523f-4350-94c6-df825d22596d (old id 1110913)
date added to LUP
2008-07-28 09:06:26
date last changed
2017-07-09 04:18:34
@article{e194c581-523f-4350-94c6-df825d22596d,
  abstract     = {A premature boy who had suffered from IRDS, bronchopulmonary dysplasia and retinopathy of prematurity developed massive hypertriglyceridemia (48.1 mmol/L) together with moderate hypercholesterolemia (12.6 mmol/L) at 5 months of age. Lipoprotein electrophoresis revealed a marked elevation of the level of the very low density lipoprotein fraction. There was a moderate decrease in the activity of a lipolytic enzyme, lipoprotein lipase (LPL). The child had neither liver or renal disorder nor any inflammatory disease. The hyperlipidemia disappeared spontaneously at the age of 3 years. The cause of the decreased LPL activity could not be established. A partial genetic deficiency in lipoprotein lipase appears the most likely explanation, since no signs of secondary lowering of LPL activity could be found.},
  author       = {Nilsson, A and Ortqvist, E and Lagercrantz, H and Nilsson-Ehle, Peter and Henter, J I},
  issn         = {1651-2227},
  keyword      = {Hypertriglyceridemia,infancy,lipoprotein lipase},
  language     = {eng},
  number       = {12},
  pages        = {1508--1510},
  publisher    = {Taylor & Francis},
  series       = {Acta Pædiatrica},
  title        = {Transient hypertriglyceridemia of infancy},
  url          = {http://dx.doi.org/10.1111/j.1651-2227.1996.tb13964.x},
  volume       = {85},
  year         = {1996},
}