Long term outcome after umbilical artery acidaemia at term birth: influence of gender and duration of fetal heart rate abnormalities
(1997) In British Journal of Obstetrics and Gynaecology 104(10). p.1123-1127- Abstract
- OBJECTIVE: To study the outcome after acidaemia at term birth, and the relation to gender and duration of pathological fetal heart rate changes. DESIGN: Population based study of 154 infants with umbilical artery pH < 7.05 at term birth. Neonatal outcome and the result of developmental screening at age four years were compared with a control group with pH > 7.10. Fetal heart rate traces in infants with acidaemia were reviewed, and the relation between duration of fetal heart rate changes and outcome was analysed. RESULTS: Of the 154 newborns with acidaemia at birth, 10 had encephalopathy, of which two died and two developed cerebral palsy. Nine of these 10 infants were boys, and eight had pH < 7.00. Male newborns (n = 39) more... (More)
- OBJECTIVE: To study the outcome after acidaemia at term birth, and the relation to gender and duration of pathological fetal heart rate changes. DESIGN: Population based study of 154 infants with umbilical artery pH < 7.05 at term birth. Neonatal outcome and the result of developmental screening at age four years were compared with a control group with pH > 7.10. Fetal heart rate traces in infants with acidaemia were reviewed, and the relation between duration of fetal heart rate changes and outcome was analysed. RESULTS: Of the 154 newborns with acidaemia at birth, 10 had encephalopathy, of which two died and two developed cerebral palsy. Nine of these 10 infants were boys, and eight had pH < 7.00. Male newborns (n = 39) more often had pronounced acidaemia (pH < 7.00) than females (n = 22). Although few infants had severe impairment, infants born with acidaemia significantly more often had speech problems at follow up than controls (19/102 versus 8/98; P = 0.03). In infants with acidaemia, duration of abnormal fetal heart rate changes was significantly associated with neonatal encephalopathy and speech problems at age four years. CONCLUSIONS: Acidaemia at term birth was associated with neonatal encephalopathy and with speech problems at four years of age. Boys had more often pronounced acidaemia and a complicated course. A protracted abnormal fetal heart rate trace was associated with poor outcome. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1111468
- author
- Ingemarsson, Ingemar LU ; Herbst, Andreas LU and Thorngren-Jerneck, Kristina LU
- organization
- publishing date
- 1997
- type
- Contribution to journal
- publication status
- published
- subject
- in
- British Journal of Obstetrics and Gynaecology
- volume
- 104
- issue
- 10
- pages
- 1123 - 1127
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:9332988
- scopus:0030924044
- ISSN
- 1365-215X
- DOI
- 10.1111/j.1471-0528.1997.tb10934.x
- language
- English
- LU publication?
- yes
- id
- e2682c7e-2efa-49d0-8b90-03923962de68 (old id 1111468)
- date added to LUP
- 2016-04-01 12:34:26
- date last changed
- 2022-01-27 06:55:14
@article{e2682c7e-2efa-49d0-8b90-03923962de68, abstract = {{OBJECTIVE: To study the outcome after acidaemia at term birth, and the relation to gender and duration of pathological fetal heart rate changes. DESIGN: Population based study of 154 infants with umbilical artery pH < 7.05 at term birth. Neonatal outcome and the result of developmental screening at age four years were compared with a control group with pH > 7.10. Fetal heart rate traces in infants with acidaemia were reviewed, and the relation between duration of fetal heart rate changes and outcome was analysed. RESULTS: Of the 154 newborns with acidaemia at birth, 10 had encephalopathy, of which two died and two developed cerebral palsy. Nine of these 10 infants were boys, and eight had pH < 7.00. Male newborns (n = 39) more often had pronounced acidaemia (pH < 7.00) than females (n = 22). Although few infants had severe impairment, infants born with acidaemia significantly more often had speech problems at follow up than controls (19/102 versus 8/98; P = 0.03). In infants with acidaemia, duration of abnormal fetal heart rate changes was significantly associated with neonatal encephalopathy and speech problems at age four years. CONCLUSIONS: Acidaemia at term birth was associated with neonatal encephalopathy and with speech problems at four years of age. Boys had more often pronounced acidaemia and a complicated course. A protracted abnormal fetal heart rate trace was associated with poor outcome.}}, author = {{Ingemarsson, Ingemar and Herbst, Andreas and Thorngren-Jerneck, Kristina}}, issn = {{1365-215X}}, language = {{eng}}, number = {{10}}, pages = {{1123--1127}}, publisher = {{Wiley-Blackwell}}, series = {{British Journal of Obstetrics and Gynaecology}}, title = {{Long term outcome after umbilical artery acidaemia at term birth: influence of gender and duration of fetal heart rate abnormalities}}, url = {{http://dx.doi.org/10.1111/j.1471-0528.1997.tb10934.x}}, doi = {{10.1111/j.1471-0528.1997.tb10934.x}}, volume = {{104}}, year = {{1997}}, }