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Epilepsiutredning. Magnettomografi allt viktigare diagnosteknik

Holtås, Stig LU and Rosén, Ingmar LU (1997) In Läkartidningen 94(23). p.2194-2200
Abstract
Electroencephalography (EEG) and neuroradiology are both indispensible techniques in cases of suspected epileptic seizure, when the aim of investigation is to determine whether the seizure was of epileptic nature, and if so whether it was the result of specific provocative factors or an expression of epileptic disease. In the latter case, the epileptic condition should be classified and its aetiology determined, if possible. Routine or sleep EEG providing interictal epileptiform discharges is a useful aid to differential diagnosis. To obtain EEG recordings during actual seizures, long-term recordings, using either ambulatory equipment or an EEG-video procedure, are usually used. The combination of EEG and video recording, using surface or... (More)
Electroencephalography (EEG) and neuroradiology are both indispensible techniques in cases of suspected epileptic seizure, when the aim of investigation is to determine whether the seizure was of epileptic nature, and if so whether it was the result of specific provocative factors or an expression of epileptic disease. In the latter case, the epileptic condition should be classified and its aetiology determined, if possible. Routine or sleep EEG providing interictal epileptiform discharges is a useful aid to differential diagnosis. To obtain EEG recordings during actual seizures, long-term recordings, using either ambulatory equipment or an EEG-video procedure, are usually used. The combination of EEG and video recording, using surface or surgically implanted electrodes, is a procedure of major importance in the evaluation of patients refractory to medical treatment and possible candidates for epilepsy surgery. In cases of epilepsy suspected to be caused by tumour or cerebrovascular disease, neurological investigation does not differ from that routinely used in such conditions. MRI (magnetic resonance imaging) techniques have become important aids in the preoperative work-up in cases of chronic therapy-resistant partial epilepsy. MRI has also simplified the identification of minor morphological abnormalities causing partial epilepsy, and is the method of choice in such cases. The sensitivity of MRI is improved by its combination with volumetric measurements and spectroscopy. The use of functional neuroimaging with SPECT (single photon emission computed tomography) and PET (positron emission tomography) during seizures provides further information. A promising new development is the co-registration of MRI and functional imaging (dipolar reconstruction of EEG spikes and seizure patterns, SPECT, PET). MRI is a cornerstone of the preoperative work-up, but diagnosis and the choice of therapeutic approach is always based on the clinical picture, EEG, and functional and morphological imaging. (Less)
Please use this url to cite or link to this publication:
author
organization
alternative title
Investigation of epilepsy. Magnetic tomography more and more important as a diagnostic technique
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Epilepsi, Magnetisk resonanstomografi, Elektroencefalografi, Positronemissionstomografi, Singelfotonemissionstomografi
in
Läkartidningen
volume
94
issue
23
pages
2194 - 2200
external identifiers
  • pmid:9213686
  • scopus:0031552424
ISSN
0023-7205
language
Swedish
LU publication?
yes
id
03cdb539-1a7a-43c2-9cd6-98d692a3ea12 (old id 1111871)
alternative location
http://ltarkiv.lakartidningen.se/artNo15892
date added to LUP
2008-07-18 14:37:29
date last changed
2017-01-01 06:54:03
@article{03cdb539-1a7a-43c2-9cd6-98d692a3ea12,
  abstract     = {Electroencephalography (EEG) and neuroradiology are both indispensible techniques in cases of suspected epileptic seizure, when the aim of investigation is to determine whether the seizure was of epileptic nature, and if so whether it was the result of specific provocative factors or an expression of epileptic disease. In the latter case, the epileptic condition should be classified and its aetiology determined, if possible. Routine or sleep EEG providing interictal epileptiform discharges is a useful aid to differential diagnosis. To obtain EEG recordings during actual seizures, long-term recordings, using either ambulatory equipment or an EEG-video procedure, are usually used. The combination of EEG and video recording, using surface or surgically implanted electrodes, is a procedure of major importance in the evaluation of patients refractory to medical treatment and possible candidates for epilepsy surgery. In cases of epilepsy suspected to be caused by tumour or cerebrovascular disease, neurological investigation does not differ from that routinely used in such conditions. MRI (magnetic resonance imaging) techniques have become important aids in the preoperative work-up in cases of chronic therapy-resistant partial epilepsy. MRI has also simplified the identification of minor morphological abnormalities causing partial epilepsy, and is the method of choice in such cases. The sensitivity of MRI is improved by its combination with volumetric measurements and spectroscopy. The use of functional neuroimaging with SPECT (single photon emission computed tomography) and PET (positron emission tomography) during seizures provides further information. A promising new development is the co-registration of MRI and functional imaging (dipolar reconstruction of EEG spikes and seizure patterns, SPECT, PET). MRI is a cornerstone of the preoperative work-up, but diagnosis and the choice of therapeutic approach is always based on the clinical picture, EEG, and functional and morphological imaging.},
  author       = {Holtås, Stig and Rosén, Ingmar},
  issn         = {0023-7205},
  keyword      = {Epilepsi,Magnetisk resonanstomografi,Elektroencefalografi,Positronemissionstomografi,Singelfotonemissionstomografi},
  language     = {swe},
  number       = {23},
  pages        = {2194--2200},
  series       = {Läkartidningen},
  title        = {Epilepsiutredning. Magnettomografi allt viktigare diagnosteknik},
  volume       = {94},
  year         = {1997},
}