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Maternal anxiety in late pregnancy and fetal hemodynamics

Sjöström, Karin LU ; Valentin, Lil LU ; Thelin, Thomas and Marsal, Karel LU (1997) In European Journal of Obstetrics, Gynecology, and Reproductive Biology 74(2). p.149-155
Abstract
The aim of this study was to investigate if fetal circulation is affected by maternal anxiety. 37 nulliparous women were studied prospectively in the third trimester of pregnancy, with self-rate tests of anxiety (STAI). Doppler ultrasound examination of the umbilical artery and fetal middle cerebral artery was performed at 37-40 gestational weeks. The pulsatility index (PI) was calculated and corrected for heart rate. The women were divided into groups of increasing levels of anxiety. The fetuses of women with high trait anxiety scores had significantly higher PI values in the umbilical artery (p = 0.0056), significantly lower PI values in the fetal middle cerebral artery (p = 0.0029) and significantly lower cerebro-umbilical PI ratios (p... (More)
The aim of this study was to investigate if fetal circulation is affected by maternal anxiety. 37 nulliparous women were studied prospectively in the third trimester of pregnancy, with self-rate tests of anxiety (STAI). Doppler ultrasound examination of the umbilical artery and fetal middle cerebral artery was performed at 37-40 gestational weeks. The pulsatility index (PI) was calculated and corrected for heart rate. The women were divided into groups of increasing levels of anxiety. The fetuses of women with high trait anxiety scores had significantly higher PI values in the umbilical artery (p = 0.0056), significantly lower PI values in the fetal middle cerebral artery (p = 0.0029) and significantly lower cerebro-umbilical PI ratios (p = 0.0002), suggesting a change in blood distribution in favor of brain circulation in the fetuses. Maternal weight, weight-increase, height, age, marital status, smoking habits, drinking habits and socio-economic factors known to affect fetal well-being did not interfere with these findings. No significant differences in birth-weight, length and head circumference were found between infants born to mothers with higher trait anxiety levels compared to mothers with lower trait anxiety levels. Our results suggest that maternal stress, in terms of trait anxiety, influences fetal cerebral circulation. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Maternal stress, Maternal anxiety, Fetal cerebral blood flow, Doppler ultrasound, STAI, Pregnancy
in
European Journal of Obstetrics, Gynecology, and Reproductive Biology
volume
74
issue
2
pages
149 - 155
publisher
Elsevier
external identifiers
  • scopus:0343247796
ISSN
0301-2115
DOI
10.1016/S0301-2115(97)00100-0
language
English
LU publication?
yes
id
d95c13cc-d389-4de4-b94f-c6dacbb10640 (old id 1112161)
date added to LUP
2008-07-21 14:06:52
date last changed
2017-07-09 03:29:53
@article{d95c13cc-d389-4de4-b94f-c6dacbb10640,
  abstract     = {The aim of this study was to investigate if fetal circulation is affected by maternal anxiety. 37 nulliparous women were studied prospectively in the third trimester of pregnancy, with self-rate tests of anxiety (STAI). Doppler ultrasound examination of the umbilical artery and fetal middle cerebral artery was performed at 37-40 gestational weeks. The pulsatility index (PI) was calculated and corrected for heart rate. The women were divided into groups of increasing levels of anxiety. The fetuses of women with high trait anxiety scores had significantly higher PI values in the umbilical artery (p = 0.0056), significantly lower PI values in the fetal middle cerebral artery (p = 0.0029) and significantly lower cerebro-umbilical PI ratios (p = 0.0002), suggesting a change in blood distribution in favor of brain circulation in the fetuses. Maternal weight, weight-increase, height, age, marital status, smoking habits, drinking habits and socio-economic factors known to affect fetal well-being did not interfere with these findings. No significant differences in birth-weight, length and head circumference were found between infants born to mothers with higher trait anxiety levels compared to mothers with lower trait anxiety levels. Our results suggest that maternal stress, in terms of trait anxiety, influences fetal cerebral circulation.},
  author       = {Sjöström, Karin and Valentin, Lil and Thelin, Thomas and Marsal, Karel},
  issn         = {0301-2115},
  keyword      = {Maternal stress,Maternal anxiety,Fetal cerebral blood flow,Doppler ultrasound,STAI,Pregnancy},
  language     = {eng},
  number       = {2},
  pages        = {149--155},
  publisher    = {Elsevier},
  series       = {European Journal of Obstetrics, Gynecology, and Reproductive Biology},
  title        = {Maternal anxiety in late pregnancy and fetal hemodynamics},
  url          = {http://dx.doi.org/10.1016/S0301-2115(97)00100-0},
  volume       = {74},
  year         = {1997},
}