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Airway symptoms and lung function in pipelayers exposed to thermal degradation products from MDI-based polyurethane.

Jakobsson, Kristina LU ; Diab, Kerstin LU ; Rylander, Lars LU and Hagmar, L (1997) In Occupational and Environmental Medicine 54. p.873-879
Abstract
OBJECTIVES: To study the prevalence of symptoms from the eyes and the upper and lower respiratory tract, lung function, and immunological sensitisation towards isocyanates in pipelayers exposed to thermal degradation products from methylene diphenyl diisocyanate (MDI)-based polyurethane (PUR). MATERIAL AND METHODS: 50 presently active and 113 formerly active pipelayers were examined. Also, 65 unexposed workers were investigated for comparison. The one year prevalence of symptoms and smoking history (questionnaire data), lung function (vital capacity (VC) and forced expiratory volume in one second (FEV1), and atopy (positive skin prick tests towards standard allergens) were assessed among pipelayers and controls. For the pipelayers, the... (More)
OBJECTIVES: To study the prevalence of symptoms from the eyes and the upper and lower respiratory tract, lung function, and immunological sensitisation towards isocyanates in pipelayers exposed to thermal degradation products from methylene diphenyl diisocyanate (MDI)-based polyurethane (PUR). MATERIAL AND METHODS: 50 presently active and 113 formerly active pipelayers were examined. Also, 65 unexposed workers were investigated for comparison. The one year prevalence of symptoms and smoking history (questionnaire data), lung function (vital capacity (VC) and forced expiratory volume in one second (FEV1), and atopy (positive skin prick tests towards standard allergens) were assessed among pipelayers and controls. For the pipelayers, the presence of work related symptoms and estimates of isocyanate and welding exposure were obtained from an interview. Skin prick tests towards specific isocyanate antigens and determinations of IgE-MDI and IgG-MDI in serum were also performed. RESULTS: The (Less)
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Contribution to journal
publication status
published
subject
in
Occupational and Environmental Medicine
volume
54
pages
873 - 879
publisher
BMJ Publishing Group
external identifiers
  • scopus:0031442378
ISSN
1470-7926
language
English
LU publication?
yes
id
bdab89ae-98b9-4314-ac7d-0910db31ec5d (old id 1112231)
alternative location
http://oem.bmj.com/cgi/content/abstract/54/12/873
date added to LUP
2008-07-21 16:19:43
date last changed
2017-01-01 06:39:28
@article{bdab89ae-98b9-4314-ac7d-0910db31ec5d,
  abstract     = {OBJECTIVES: To study the prevalence of symptoms from the eyes and the upper and lower respiratory tract, lung function, and immunological sensitisation towards isocyanates in pipelayers exposed to thermal degradation products from methylene diphenyl diisocyanate (MDI)-based polyurethane (PUR). MATERIAL AND METHODS: 50 presently active and 113 formerly active pipelayers were examined. Also, 65 unexposed workers were investigated for comparison. The one year prevalence of symptoms and smoking history (questionnaire data), lung function (vital capacity (VC) and forced expiratory volume in one second (FEV1), and atopy (positive skin prick tests towards standard allergens) were assessed among pipelayers and controls. For the pipelayers, the presence of work related symptoms and estimates of isocyanate and welding exposure were obtained from an interview. Skin prick tests towards specific isocyanate antigens and determinations of IgE-MDI and IgG-MDI in serum were also performed. RESULTS: The},
  author       = {Jakobsson, Kristina and Diab, Kerstin and Rylander, Lars and Hagmar, L},
  issn         = {1470-7926},
  language     = {eng},
  pages        = {873--879},
  publisher    = {BMJ Publishing Group},
  series       = {Occupational and Environmental Medicine},
  title        = {Airway symptoms and lung function in pipelayers exposed to thermal degradation products from MDI-based polyurethane.},
  volume       = {54},
  year         = {1997},
}