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Does long-term smoking affect aortic stiffness more in women than in men?

Sonesson, Björn LU ; Rydén Ahlgren, Åsa LU ; Lazer, L and Länne, T (1997) In Clinical Physiology 17(5). p.439-447
Abstract
Smoking is a well-known risk factor for cardiovascular disease, although understanding of the pathophysiological mechanism is incomplete. The effect of heavy smoking, for more than 20 years and of 20 cigarettes per day, on aortic stiffness was studied in women (n = 23, age range 43-61 years) and men (n = 21, age range 43-61 years) who smoked but were otherwise healthy and compared with a healthy reference population that did not smoke. Aortic stiffness (beta) was calculated from the diameter and the pulsatile diameter change determined non-invasively using an ultrasonic echo-tracking system and blood pressure obtained by the auscultatory method. The results showed that aortic diameter did not differ in smoking males (P = 0.974) or in... (More)
Smoking is a well-known risk factor for cardiovascular disease, although understanding of the pathophysiological mechanism is incomplete. The effect of heavy smoking, for more than 20 years and of 20 cigarettes per day, on aortic stiffness was studied in women (n = 23, age range 43-61 years) and men (n = 21, age range 43-61 years) who smoked but were otherwise healthy and compared with a healthy reference population that did not smoke. Aortic stiffness (beta) was calculated from the diameter and the pulsatile diameter change determined non-invasively using an ultrasonic echo-tracking system and blood pressure obtained by the auscultatory method. The results showed that aortic diameter did not differ in smoking males (P = 0.974) or in smoking females (P = 0.361). Aortic stiffness was increased in the female (P = 0.041) but not male smokers (P = 0.222). Systolic, mean and diastolic blood pressure in the men and women who smoked did not differ from those in the healthy reference population. In conclusion, this investigation shows increased aortic stiffness in female but not in male smokers. It indicates that the aorta of women might be more vulnerable to smoking with regard to stiffening and degeneration than the aorta of men. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
gender differences, echo-tracking ultrasonography, cigarette compliance, arterial distensibility
in
Clinical Physiology
volume
17
issue
5
pages
439 - 447
publisher
Wiley-Blackwell
external identifiers
  • pmid:9347193
  • scopus:0030866418
ISSN
1365-2281
DOI
10.1046/j.1365-2281.1997.04848.x
language
English
LU publication?
yes
id
8f6017db-ae39-4f82-b1ce-c489a0fe1381 (old id 1112248)
date added to LUP
2008-07-21 16:30:34
date last changed
2017-01-01 05:02:20
@article{8f6017db-ae39-4f82-b1ce-c489a0fe1381,
  abstract     = {Smoking is a well-known risk factor for cardiovascular disease, although understanding of the pathophysiological mechanism is incomplete. The effect of heavy smoking, for more than 20 years and of 20 cigarettes per day, on aortic stiffness was studied in women (n = 23, age range 43-61 years) and men (n = 21, age range 43-61 years) who smoked but were otherwise healthy and compared with a healthy reference population that did not smoke. Aortic stiffness (beta) was calculated from the diameter and the pulsatile diameter change determined non-invasively using an ultrasonic echo-tracking system and blood pressure obtained by the auscultatory method. The results showed that aortic diameter did not differ in smoking males (P = 0.974) or in smoking females (P = 0.361). Aortic stiffness was increased in the female (P = 0.041) but not male smokers (P = 0.222). Systolic, mean and diastolic blood pressure in the men and women who smoked did not differ from those in the healthy reference population. In conclusion, this investigation shows increased aortic stiffness in female but not in male smokers. It indicates that the aorta of women might be more vulnerable to smoking with regard to stiffening and degeneration than the aorta of men.},
  author       = {Sonesson, Björn and Rydén Ahlgren, Åsa and Lazer, L and Länne, T},
  issn         = {1365-2281},
  keyword      = {gender differences,echo-tracking ultrasonography,cigarette compliance,arterial distensibility},
  language     = {eng},
  number       = {5},
  pages        = {439--447},
  publisher    = {Wiley-Blackwell},
  series       = {Clinical Physiology},
  title        = {Does long-term smoking affect aortic stiffness more in women than in men?},
  url          = {http://dx.doi.org/10.1046/j.1365-2281.1997.04848.x},
  volume       = {17},
  year         = {1997},
}