Does long-term smoking affect aortic stiffness more in women than in men?
(1997) In Clinical Physiology 17(5). p.439-447- Abstract
- Smoking is a well-known risk factor for cardiovascular disease, although understanding of the pathophysiological mechanism is incomplete. The effect of heavy smoking, for more than 20 years and of 20 cigarettes per day, on aortic stiffness was studied in women (n = 23, age range 43-61 years) and men (n = 21, age range 43-61 years) who smoked but were otherwise healthy and compared with a healthy reference population that did not smoke. Aortic stiffness (beta) was calculated from the diameter and the pulsatile diameter change determined non-invasively using an ultrasonic echo-tracking system and blood pressure obtained by the auscultatory method. The results showed that aortic diameter did not differ in smoking males (P = 0.974) or in... (More)
- Smoking is a well-known risk factor for cardiovascular disease, although understanding of the pathophysiological mechanism is incomplete. The effect of heavy smoking, for more than 20 years and of 20 cigarettes per day, on aortic stiffness was studied in women (n = 23, age range 43-61 years) and men (n = 21, age range 43-61 years) who smoked but were otherwise healthy and compared with a healthy reference population that did not smoke. Aortic stiffness (beta) was calculated from the diameter and the pulsatile diameter change determined non-invasively using an ultrasonic echo-tracking system and blood pressure obtained by the auscultatory method. The results showed that aortic diameter did not differ in smoking males (P = 0.974) or in smoking females (P = 0.361). Aortic stiffness was increased in the female (P = 0.041) but not male smokers (P = 0.222). Systolic, mean and diastolic blood pressure in the men and women who smoked did not differ from those in the healthy reference population. In conclusion, this investigation shows increased aortic stiffness in female but not in male smokers. It indicates that the aorta of women might be more vulnerable to smoking with regard to stiffening and degeneration than the aorta of men. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1112248
- author
- Sonesson, Björn LU ; Rydén Ahlgren, Åsa LU ; Lazer, L and Länne, T
- organization
- publishing date
- 1997
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- gender differences, echo-tracking ultrasonography, cigarette compliance, arterial distensibility
- in
- Clinical Physiology
- volume
- 17
- issue
- 5
- pages
- 439 - 447
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:9347193
- scopus:0030866418
- ISSN
- 1365-2281
- DOI
- 10.1046/j.1365-2281.1997.04848.x
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Emergency medicine/Medicine/Surgery (013240200), Clinical Physiology and Nuclear Medicine Unit (013242320)
- id
- 8f6017db-ae39-4f82-b1ce-c489a0fe1381 (old id 1112248)
- date added to LUP
- 2016-04-01 12:19:12
- date last changed
- 2023-09-02 03:29:08
@article{8f6017db-ae39-4f82-b1ce-c489a0fe1381, abstract = {{Smoking is a well-known risk factor for cardiovascular disease, although understanding of the pathophysiological mechanism is incomplete. The effect of heavy smoking, for more than 20 years and of 20 cigarettes per day, on aortic stiffness was studied in women (n = 23, age range 43-61 years) and men (n = 21, age range 43-61 years) who smoked but were otherwise healthy and compared with a healthy reference population that did not smoke. Aortic stiffness (beta) was calculated from the diameter and the pulsatile diameter change determined non-invasively using an ultrasonic echo-tracking system and blood pressure obtained by the auscultatory method. The results showed that aortic diameter did not differ in smoking males (P = 0.974) or in smoking females (P = 0.361). Aortic stiffness was increased in the female (P = 0.041) but not male smokers (P = 0.222). Systolic, mean and diastolic blood pressure in the men and women who smoked did not differ from those in the healthy reference population. In conclusion, this investigation shows increased aortic stiffness in female but not in male smokers. It indicates that the aorta of women might be more vulnerable to smoking with regard to stiffening and degeneration than the aorta of men.}}, author = {{Sonesson, Björn and Rydén Ahlgren, Åsa and Lazer, L and Länne, T}}, issn = {{1365-2281}}, keywords = {{gender differences; echo-tracking ultrasonography; cigarette compliance; arterial distensibility}}, language = {{eng}}, number = {{5}}, pages = {{439--447}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Clinical Physiology}}, title = {{Does long-term smoking affect aortic stiffness more in women than in men?}}, url = {{http://dx.doi.org/10.1046/j.1365-2281.1997.04848.x}}, doi = {{10.1046/j.1365-2281.1997.04848.x}}, volume = {{17}}, year = {{1997}}, }